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Scholar Results 1 - 10 of about 101 related to Lehtinen: Association of NOS1AP genetic variants with QT interval duration in families from.... (0.13 sec) 

Association of NOS1AP genetic variants with QT interval duration in families from the …


AB Lehtinen, C Newton-Cheh, JT Ziegler, CD … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—In European Americans, rs10494366 minor homozygotes had a
9.3-ms-longer QT interval compared with major homozygotes (P = 5.7 × 10 −5 );
rs10918594 minor homozygotes had a 12.5-ms-longer QT interval compared with ...
Cited by 24 - Related articles - BL Direct - All 4 versions

Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac …

- oxfordjournals.org
MD Tobin, M Kahonen, P Braund, T Nieminen, … - International Journal of Epidemiology, 2008 - IEA
1 Department of Health Sciences, University of Leicester, UK, LE1 7RH. 2
Department of Genetics, University of Leicester, UK, LE1 7RH. 3 Department of
Clinical Physiology, Tampere University Hospital and Medical School, ...
Cited by 19 - Related articles - All 7 versions

Identification of a common variant at the NOS1AP locus strongly associated to QT-interval …

- nursing2008.com
M Eijgelsheim, ALHJ Aarnoudse, F Rivadeneira … - Human Molecular Genetics, 2009 - Oxford Univ Press
QT-interval prolongation is an electrophysiologic phenomenon associated with
sudden cardiac death. The QT-interval in the general population is 35%
heritable. In genome-wide association studies, a common variant ...
Cited by 12 - Related articles - All 6 versions

Associations between genetic variants in the NOS1AP (CAPON) gene and cardiac …

- umaryland.edu [PDF] 
W Post, H Shen, C Damcott, DE Arking, WHL … - Hum Hered, 2007 - content.karger.com
Page 1. Fax +41 61 306 12 34 E-Mail karger@karger.ch www.karger.com Original
Paper Hum Hered 2007;64:214–219 DOI: 10.1159/000103630 ...
Cited by 38 - Related articles - BL Direct - All 7 versions

Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam …

- ahajournals.org
AJLHJ Aarnoudse, C Newton-Cheh, PIW de … - Circulation, 2007 - Am Heart Assoc
From the Departments of Epidemiology and Biostatistics (ALHJA, SMJMS, AH, AGU,
JCMW, BHCS), Internal Medicine (AGU, BHCS), and Medical Informatics (JAK),
Erasmus Medical Center, Rotterdam, the Netherlands; Cardiology Division ...
Cited by 62 - Related articles - All 5 versions

Common variation in NOS1AP and KCNH2 genes and QT interval duration in young adults. …


OT Raitakari, J Blom-Nyholm, TA Koskinen, M … - Annals of Medicine, 2009 - informahealthcare.com
Results: The NOS1AP variant was significantly related with heart rate-corrected
QT interval duration (QTc). Additive regression model adjusting for age, sex,
systolic blood pressure, body mass index, alcohol use, and smoking ...
Cited by 11 - Related articles - All 6 versions

CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the …


KC Chang, AS Barth, T Sasano, E Kizana, Y … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences
Congenital long- or short-QT syndrome may lead to life-threatening ventricular
tachycardia and sudden cardiac death. Apart from the rare disease-causing
mutations, common genetic variants in CAPON, a neuronal nitric oxide ...
Cited by 19 - Related articles - BL Direct - All 8 versions

[PDF] Common variants at ten loci influence QT interval duration in the QTGEN Study


C Newton-Cheh, M Eijgelsheim, KM Rice, PI De … - Nat Genet, 2009 - massgeneral.org
QT interval duration, reflecting myocardial repolarization on the
electrocardiogram, is a heritable risk factor for sudden cardiac death and
drug-induced arrhythmias. We conducted a meta-analysis of three genome-wide ...
Cited by 17 - Related articles - View as HTML - All 7 versions

Common variants at ten loci modulate the QT interval duration in the QTSCD Study


A Pfeufer, S Sanna, DE Arking, M Müller, V … - Nature Genetics, 2009 - nature.com
The QT interval, a measure of cardiac repolarization, predisposes to ventricular
arrhythmias and sudden cardiac death (SCD) when prolonged or shortened. A common
variant in NOS1AP is known to influence repolarization. We analyze ...
Cited by 18 - Related articles - All 3 versions

Common genetic variation in KCNH2 is associated with QT interval duration. The …

- ahajournals.org [PDF] 
C Newton-Cheh, CY Guo, MG Larson, SL Musone … - Circulation, 2007 - Am Heart Assoc
Christopher Newton-Cheh, MD, MPH; Chao-Yu Guo, PhD; Martin G. Larson, ScD; Stacy
L. Musone, BA; Aarti Surti, BA; Amy L. Camargo, BA; Jared A. Drake, BA; Emelia
J. Benjamin, MD, ScM; Daniel Levy, MD; Ralph B. D'Agostino, Sr, PhD; Joel ...
Cited by 32 - Related articles - All 7 versions


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