GM Brodie, M Wallberg, P Santamaria, FS … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS—RIP-TNFα-NOD mice were crossed to
B-cell–deficient NOD mice, and diabetes development was monitored. We used in
vitro antigen presentation assays and in vivo administration of ... Cited by 12 - Related articles - BL Direct - All 3 versions
EA Green - Am Diabetes Assoc Gillian M. Brodie, BSc1, Maja Wallberg, PhD1, Pere Santamaria, MD, PhD2, F.
Susan Wong, MBBS, PhD3 and E. Allison Green, PhD1 Brodie GM and Wallberg M,
contributed equally to this manuscript. ... 1Department of Pathology, ... Related articles
- ►diabetesjournals.org E Mariño, M Batten, J Groom, S Walters, D … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We demonstrate that splenic MZB numbers in female NOD mice undergo a
marked, approximately threefold expansion between ∼12 and 16 weeks of age,
coincident with the onset of frank diabetes. Functionally, NOD MZBs are ... Cited by 8 - Related articles - BL Direct - All 3 versions
A Willcox, SJ Richardson, AJ Bone, AK … - Clin Exp Immunol, 2009 - interscience.wiley.com The immunopathology of type 1 diabetes (T1D) has proved difficult to study in
man because of the limited availability of appropriate samples, but we now
report a detailed study charting the evolution of insulitis in human T1D. ... Cited by 6 - Related articles - All 3 versions
- ►jimmunol.org PA Silveira, HD Chapman, J Stolp, E Johnson … - The Journal of Immunology, 2006 - Am Assoc Immnol Autoreactive T cells clearly mediate the pancreatic β cell destruction causing
type 1 diabetes (T1D). However, studies in NOD mice indicate that B cells also
contribute to pathogenesis because their ablation by introduction of an ... Cited by 7 - Related articles - BL Direct - All 4 versions
FD Dufour, AG Baxter, PA Silveira - Journal of Immunotoxicology, 2008 - informahealthcare.com Type 1 diabetes is one of the most prevalent autoimmune conditions that develops
during childhood and has an increasing incidence worldwide. The disease results
from the destruction of pancreatic β cells mediated by autoreactive T- ... Cited by 2 - Related articles - All 7 versions
- ►jimmunol.org G Chamberlain, M Wallberg, D Rainbow, K … - The Journal of Immunology, 2006 - Am Assoc Immnol Identification of candidate genes and their immunological mechanisms that
control autoaggressive T cells in inflamed environments, may lead to novel
therapies for autoimmune diseases, like type 1 diabetes (T1D). In this ... Cited by 3 - Related articles - BL Direct - All 4 versions
L Yu, GS Eisenbarth - Immunology of type 1 diabetes, 2004 - books.google.com CHAPTER 10 Humoral Autoimmunity Liping Yu and George S. Eisenbarth A litde more
than a decade ago, screening for autoantibodies associated with Type 1A (immune
mediated) diabetes was limired ro measuring cytoplasmic islet cell ... Cited by 11 - Related articles - All 3 versions
F Wong, L Siew, L Wen - Biochemical Society Transactions, 2008 - biochemsoctrans.org The autoimmune attack on pancreatic β-cells is orchestrated by a variety of
cells that produce cytokines and other toxic mediators. CD8 + T-cells work
together with other lymphocytes and antigen-presenting cells to mediate ... Cited by 4 - Related articles - Cached - BL Direct - All 4 versions
G Zekavat, SY Rostami, A Badkerhanian, RF … - The Journal of Immunology, 2008 - Am Assoc Immnol B lymphocytes are required for the pathogenesis of autoimmune diabetes in NOD
mice. Previous studies established that a lymphopenic transitional (TR) B cell
compartment reduces the competitive constraint on the entry of newly ... Cited by 6 - Related articles - All 4 versions
