H Tsui, Y Chan, L Tang, S Winer, RK Cheung, G … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— pSC cultures did not express major histocompatibility complex (MHC) class II and
were lysed by ex vivo CTLs from diabetic NOD mice. In vivo, restoration of MHC class I in
GFAP-β2m transgenics significantly accelerated adoptively transferred diabetes. Target ... Cited by 4 - Related articles - BL Direct - All 4 versions
- ►jbc.org AY Savinov, DV Rozanov, AY Strongin - Journal of Biological Chemistry, 2007 - ASBMB Human diabetes mellitus (IDDM; type I diabetes) is a T cell-mediated disease that is closely modeled
in non-obese diabetic (NOD) mice. The pathogenesis of IDDM involves the transmigration of
autoimmune T cells into the pancreatic islets and the subsequent destruction of insulin- ... Cited by 3 - Related articles - All 4 versions
EM Zeinstra, N Wilczak, JC Wilschut, L Glazenburg, … - Journal of …, 2006 - Elsevier A failure of tight control of MHC class II expression on astrocytes may play a role in the development
of autoimmune responses in multiple sclerosis. The 5-HT 4 serotonin receptor agonists cisapride
and prucalopride, at concentrations between 10 − 10 M and 10 − 8 M, reduced ... Cited by 4 - Related articles - All 10 versions
CD Sharp, M Huang, J Glawe, DR Patrick, S Pardue, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—TNF- significantly increased NOD/LtJ T-cell adhesion, which was completely blocked
by SDF-1 in a dose-dependent manner, revealing a novel chemorepulsive effect.
Conversely, SDF-1 enhanced C57BL/6J T-cell adhesion to TNF- –activated islet ... Cited by 4 - Related articles - BL Direct - All 4 versions
I Guleria, M Gubbels Bupp, S Dada, B Fife, Q Tang, MJ … - Clinical Immunology, 2007 - Elsevier The PD-1–PDL1 pathway plays a critical role in regulating autoimmune diabetes as blockade
or deficiency of PD-1 or PDL1 results in accelerated disease in NOD mice. We explored the cellular
mechanisms involved in the regulation of these autoimmune responses by investigations ... Cited by 5 - Related articles - All 2 versions
D Yadav, C Fine, M Azuma, N Sarvetnick - Molecular immunology, 2007 - Elsevier Costimulation by B7-1 and B7-2 molecules results in divergent biological effects. This is particularly
striking in the NOD mouse, since the lack of B7-2 leads to complete protection from diabetes
whereas the B7-1 deficiency causes exacerbation of disease. We tested the hypothesis ... Cited by 6 - Related articles - All 3 versions
Y Tsuyuki, H Fujimaki, N Hikawa, K Fujita, T Nagata, M … - Neuroreport, 1998 - journals.lww.com Schwann cells (SCs) are the glial cells that character- ize the peripheral nervous system
(PNS), and corres- pond to oligodendroglia cells in the central nervous system (CNS). They become
aligned along the axonal processes and form myelin sheath to protect neurons to ... Cited by 15 - Related articles - BL Direct - All 3 versions
- ►cell.com H Tsui, R Razavi, Y Chan, J Yantha, HM Dosch - Trends in Molecular Medicine, 2007 - Elsevier Type 1 diabetes (T1D) results from autoimmune-mediated loss of insulin-producing β-cells. Recent
findings suggest that the events controlling T1D development are not only immunological, but
also neuronal in nature. In the non-obese diabetic (NOD) mouse model of T1D, a mutant ... Cited by 8 - Related articles - All 4 versions
- ►diabetesjournals.org J Carrillo, MC Puertas, A Alba, RM Ampudia, X Pastor, … - Diabetes, 2005 - Am Diabetes Assoc B-cells accumulate in pancreatic islets during the autoimmune response that precedes the onset
of type 1 diabetes. However, the role and antigenic specificity of these cells remain a
mystery. To elucidate the antigenic repertoire of islet-infiltrating B-cells in type 1 diabetes, ... Cited by 14 - Related articles - All 6 versions
