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Scholar Results 1 - 10 of about 101 related to Cano: Regulated β-cell regeneration in the adult mouse pancreas. (0.12 sec) 

Regulated β-cell regeneration in the adult mouse pancreas

- diabetesjournals.org
DA Cano, IC Rulifson, PW Heiser, LB Swigart, S … - Diabetes, 2008 - Am Diabetes Assoc
Several studies have shown that the adult pancreas possesses a limited potential for β-cell
regeneration upon tissue injury. One of the difficulties in studying β-cell regeneration has been
the lack of a robust, synchronized ...
Cited by 15 - Related articles - BL Direct - All 3 versions

HES-1 Is Involved in Adaptation of Adult Human β-Cells to Proliferation In Vitro


Y Bar, HA Russ, S Knoller, L Ouziel-Yahalom, S Efrat - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—In vitro expansion of β-cells from adult human islets could solve the tissue shortage
for cell replacement therapy of diabetes. Culture of human islet cells typically results in <16 cell
doublings and loss of insulin ...
Cited by 3 - Related articles - All 4 versions

Animal models of human type 1 diabetes


M von Herrath, GT Nepom - Nature Immunology, 2009 - nature.com
Type 1 diabetes is an immune-mediated disease in which pancreatic insulin-producing beta cells are
damaged and destroyed. Animal models have served a prominent function in the development of the
present ideas of pathogenesis and ...
Cited by 4 - Related articles - All 3 versions

Generation and expansion of multipotent mesenchymal progenitor cells from …


R Gallo, F Gambelli, B Gava, F Sasdelli, V Tellone … - Cell Death & …, 2007 - nature.com
Cellular models and culture conditions for in vitro expansion of insulin-producing cells represent a
key element to develop cell therapy for diabetes. Initial evidence that human -cells could be
expanded after undergoing a ...
Cited by 14 - Related articles - BL Direct - All 5 versions

" Humanized" HLA Transgenic NOD Mice to Identify Pancreatic β Cell Autoantigens …


DV SERREZE, MP MARRON, TP … - Annals of the New York …, 2007 - interscience.wiley.com
Abstract : The mechanistic basis by which the H2 g7 major histocompatibility complex (MHC) provides
the primary risk factor for the development of T cell–mediated autoimmune type 1 diabetes (T1D) in
non-obese diabetic (NOD) mice ...
Cited by 3 - Related articles - BL Direct - All 5 versions

Cadherin Switching and Activation of {beta}-Catenin Signaling Underlie …


GV Shah, A Muralidharan, M Gokulgandhi, K Soan, … - Journal of Biological …, 2009 - ASBMB
Calcitonin, a neuroendocrine peptide, and its receptor are localized in the basal epithelium of
benign prostate but in the secretory epithelium of malignant prostates. The abundance of calcitonin
and calcitonin receptor mRNA ...
Cited by 3 - Related articles - All 3 versions

Acquisition of epithelial-mesenchymal transition phenotype of gemcitabine- …


Z Wang, Y Li, D Kong, S Banerjee, A Ahmad, AS Azmi, … - Cancer research, 2009 - AACR
Pancreatic cancer (PC) is a highly aggressive malignant disease, which is ranked as the fourth
leading cause of cancer-related deaths in the United States, with 37,000 newly diagnosed cases and
34,000 deaths per year in the ...
Cited by 4 - Related articles - All 4 versions

PANIC-ATTAC: A Mouse Model for Inducible and Reversible β-Cell Ablation

- diabetesjournals.org
ZV Wang, J Mu, TD Schraw, L Gautron, JK Elmquist, BB … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Islet transplantations have been performed clinically, but their practical applications
are limited. An extensive effort has been made toward the identification of pancreatic β-cell stem
cells that has yielded many ...
Cited by 4 - Related articles - All 4 versions

Scurfy, the Foxp3 locus, and the molecular basis of peripheral tolerance.

- unair.ac.id [PDF] 
MW Appleby, F Ramsdell - Curr Top Microbiol Immunol, 2008 - Springer
Abstract The ability to rapidly and efficiently recognize and eliminate pathogens while sparing
normal self tissue is a hallmark of the mammalian immune system. When it fails, however, autoimmune
disease results. The genetic and ...
Cited by 4 - Related articles - All 4 versions

Epithelial–mesenchymal transition in cancer metastasis: Mechanisms, markers and …


A Voulgari, A Pintzas - BBA-Reviews on Cancer, 2009 - Elsevier
Epithelial–mesenchymal transition (EMT) is a key step during embryogenesis. Accumulating evidence
suggests a critical role in cancer progression, through which tissue epithelial cancers invade and
metastasise. Cell characteristics ...
Cited by 5 - Related articles - All 2 versions


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