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Scholar Results 1 - 10 of about 101 related to Toledo: Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite.... (0.08 sec) 

Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases …


FGS Toledo, EV Menshikova, K Azuma, Z … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE— In obesity and type 2 diabetes, exercise combined with weight loss
increases skeletal muscle mitochondrial capacity. It remains unclear whether
mitochondrial capacity increases because of weight loss, improvements in ...
Cited by 20 - Related articles - BL Direct - All 5 versions

Asian Indians have enhanced skeletal muscle mitochondrial capacity to produce ATP in …

- diabetesjournals.org
KS Nair, ML Bigelow, YW Asmann, LS Chow, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— The glucose infusion rates required to maintain identical glucose
levels during the similar insulin infusion rates were substantially lower in
diabetic Indians than in the nondiabetic participants (P < 0.001), and they ...
Cited by 30 - Related articles - BL Direct - All 4 versions

Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship …

- diabetesjournals.org
FGS Toledo, EV Menshikova, VB Ritov, K … - Diabetes, 2007 - Am Diabetes Assoc
OBJECTIVE— Reduced mitochondrial capacity in skeletal muscle occurs in type 2
diabetic patients and in those at increased risk for this disorder, but the
extent to which mitochondrial dysfunction in type 2 diabetic patients is ...
Cited by 49 - Related articles - BL Direct - All 5 versions

Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle

- nih.gov
R Boushel, E Gnaiger, P Schjerling, M … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Insulin resistance and type 2 diabetes are associated
with mitochondrial dysfunction. The aim of the present study was to test the
hypothesis that oxidative phosphorylation and electron transport capacity ...
Cited by 79 - Related articles - BL Direct - All 9 versions

Early or advanced stage type 2 diabetes is not accompanied by in vivo skeletal muscle …

- eje.org
HM De Feyter, NMA van den Broek, SFE Praet, … - European Journal of Endocrinology, 2008 - eje.org
Objective: Several lines of evidence support a potential role of skeletal muscle
mitochondrial dysfunction in the pathogenesis of insulin resistance and/or type
2 diabetes. However, it remains to be established whether mitochondrial ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not …

- physiology.org
GP Holloway, A Thrush, GJF Heigenhauser, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
A reduction in fatty acid oxidation has been associated with lipid accumulation
and insulin resistance in the skeletal muscle of obese individuals. We examined
whether this decrease in fatty acid oxidation was attributable to a ...
Cited by 23 - Related articles - BL Direct - All 7 versions

Increased daily walking improves lipid oxidation without changes in mitochondrial function …

- diabetesjournals.org
MI Trenell, KG Hollingsworth, EL Lim, R … - Diabetes care, 2008 - Am Diabetes Assoc
RESULTS—Baseline physical activity (6,450 ± 851 vs. 7,638 ± 741 steps/day),
basal ATP use (12 ± 1 vs. 12 ± 1 µmol · ml –1 · min –1 ),
phosphocreatine recovery from exercise (31 ± 5 vs. 29 ± 3 s), and basal ...
Cited by 3 - Related articles - All 7 versions

Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear- …

- physiology.org
E De Filippis, G Alvarez, R Berria, K Cusi, S … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Mitochondrial dysfunction, associated with insulin resistance, is characterized
by low expression of peroxisome proliferator-activated receptor- coactivator-1
(PGC-1 ) and nuclear-encoded mitochondrial genes. This deficit could be due ...
Cited by 14 - Related articles - BL Direct - All 3 versions

Effect of aging on glucose homeostasis

- Free from Publisher
E Szoke, MZ Shrayyef, S Messing, HJ Woerle, … - Diabetes Care, 2008 - Am Diabetes Assoc
RESULTS—As expected, both phases of insulin release and insulin sensitivity
were reduced in individuals with IGT (all P < 0.01). Insulin sensitivity was not
independently correlated with age in either group. In people with NGT, the ...
Cited by 13 - Related articles - BL Direct - All 4 versions

Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript …

- shouxi.net
YW Asmann, CS Stump, KR Short, JM Coenen- … - Diabetes, 2006 - Am Diabetes Assoc
We investigated whether previously reported muscle mitochondrial dysfunction and
altered gene transcript levels in type 2 diabetes might be secondary to abnormal
blood glucose and insulin levels rather than an intrinsic defect of type 2 ...
Cited by 49 - Related articles - BL Direct - All 5 versions


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