MJ Richer, N Straka, D Fang, I Shanina, MS … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Coxsackievirus infections have long been associated with the
induction of type 1 diabetes. Infection with coxsackievirus B4 (CB4) enhances
type 1 diabetes onset in NOD mice by accelerating the presentation of ... Cited by 9 - Related articles - BL Direct - All 4 versions
AC Anderson, R Chandwaskar, DH Lee, VK … - The Journal of Immunology, 2008 - Am Assoc Immnol The Idd3 genetic interval confers protection against multiple autoimmune
diseases, including type 1 diabetes and experimental autoimmune
encephalomyelitis. The favored candidate gene in this interval is Il2, ... Cited by 6 - Related articles - All 2 versions
LSK Walker - Expert Opin. Biol. Ther., 2008 - informahealthcare.com Background: The critical role for regulatory T cells (Treg) in suppressing
autoimmune pathology is now well recognised. However, the extent to which
defects in regulation can be blamed for the onset of diseases like type 1 ... Cited by 3 - Related articles - All 5 versions
MJ Richer, MS Horwitz - Frontiers in bioscience: a journal and virtual library, 2008 - ncbi.nlm.nih.gov Susceptibility to autoimmune diseases is dictated by a complex interplay of
genetic determinants and environmental factors. Viral infections have long been
suspected to be involved in the etiology of several autoimmune disorders. ... Cited by 11 - Related articles
MJ Richer, DJ Lavallée, I Shanina, MS … - PLoS One, 2009 - pubmedcentral.nih.gov Toll-like receptor 3 (TLR3) has been proposed to play a central role in the
early recognition of viruses by sensing double stranded RNA, a common
intermediate of viral replication. However, several reports have ... Cited by 6 - Related articles - All 7 versions
- ►diabetesjournals.org [PDF] MJ Richer, N Straka, D Fang, I Shanina, MS … - Diabetes, 2008 - Am Diabetes Assoc Page 1. Regulatory T cells protect from type 1 diabetes following induction
by coxsackievirus infection in the context of TGF-β. ... Cited by 1 - Related articles - All 2 versions
- ►diabetesjournals.org CM Filippi, AE Juedes, JE Oldham, E Ling, L … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Surprisingly, when expressed selectively in the pancreas, TGF-β
reduced apoptosis of differentiated autoreactive CD8 + T-cells, favoring their
expansion and infiltration of the islets. These results pointed to ... Cited by 4 - Related articles - All 4 versions
MS Horwitz, A Ilic, C Fine, N Sarvetnick - Journal of Autoimmunity, 2005 - Elsevier Chronic myocarditis often progresses to dilated cardiomyopathy resulting in
heart failure or cardiac transplantation. Viral infection is the most common
cause of myocarditis and coxsackie B viruses (CBV) are the most frequently ... Cited by 5 - Related articles - All 3 versions
- ►nih.gov AO Weinzierl, G Szalay, H Wolburg, M Sauter … - Journal of Virology, 2008 - Am Soc Microbiol Enteroviruses such as coxsackievirus B3 (CVB3) are able to induce lethal acute
and chronic myocarditis. In resistant C57BL/6 mice, CVB3 myocarditis is
abrogated by T-cell-dependent mechanisms, whereas major histocompatibility ... Cited by 6 - Related articles - All 6 versions
