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Scholar Results 1 - 10 of about 101 related to Forbes: Oxidative stress as a major culprit in kidney disease in diabetes. (0.12 sec) 

Oxidative stress as a major culprit in kidney disease in diabetes

- diabetesjournals.org
JM Forbes, MT Coughlan, ME Cooper - Diabetes, 2008 - Am Diabetes Assoc
It is postulated that localized tissue oxidative stress is a key component in
the development of diabetic nephropathy. There remains controversy, however, as
to whether this is an early link between hyperglycemia and renal disease or ...
Cited by 43 - Related articles - All 3 versions

Telmisartan, an Angiotensin II Type 1 Receptor Blocker, Inhibits Advanced Glycation End- …


T Matsui, S Yamagishi, S Ueda, K Nakamura, … - The Journal of international medical research, 2007 - ingentaconnect.com
Interaction between advanced glycation end-products (AGEs) and their receptor
(RAGE) plays a central role in diabetic nephropathy pathogenesis.
Pathophysiological crosstalk between the AGEs-RAGE system and angiotensin ...
Cited by 20 - Related articles - BL Direct - All 4 versions

LR-90 prevents dyslipidaemia and diabetic nephropathy in the Zucker diabetic fatty rat


JL Figarola, S Loera, Y Weng, N Shanmugam, … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis Previous studies have shown that LR-90, a new inhibitor
of AGE formation, prevented the develop- ment of experimental type 1 diabetic
nephropathy. In this study, we examined the effects of LR-90 in the Zucker ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Oxidative stress and advanced glycation in diabetic nephropathy


MT Coughlan, AL Mibus, JM Forbes - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2008 - interscience.wiley.com
Nephropathy remains a significant cause of morbidity and mortality in the
diabetic population and is the leading cause of end-stage renal failure in the
Western World. As a result of the diabetic milieu, increased generation of ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Analysis of NO-synthase expression and clinical risk factors in human diabetic nephropathy

- oxfordjournals.org
B Hohenstein, CPM Hugo, B Hausknecht, KP … - Nephrology Dialysis Transplantation, 2007 - ERA-EDTA
Results. The mean age of patients at biopsy was 60.3 years and the mean duration
of diabetes 12.9 years. Expression of cortical and glomerular eNOS was increased
in type 2 diabetes (P < 0.05). Increased expression of glomerular and ...
Cited by 8 - Related articles - BL Direct - All 7 versions

Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in …

- ahajournals.org [PDF] 
P Lewis, N Stefanovic, J Pete, AC Calkin, S … - Circulation, 2007 - Am Heart Assoc
Paul Lewis, BSc, LLB (Hons); Nada Stefanovic, BSc; Josefa Pete, BSc (Hons); Anna
C. Calkin, PhD; Sara Giunti, MD, PhD; Vicki Thallas-Bonke, BAppSci; Karin A.
Jandeleit-Dahm, MD, PhD; Terri J. Allen, PhD; Ismail Kola, PhD; Mark E. ...
Cited by 25 - Related articles - All 8 versions

Vascular endothelial dysfunction: A tug of war in diabetic nephropathy?


P Balakumar, VA Chakkarwar, P Krishan, M … - Biomedicine & Pharmacotherapy, 2009 - Elsevier
Vascular endothelium regulates vascular tone and maintains free flow of blood in
vessels. Vascular endothelial dysfunction (VED) results in reduced activation of
endothelial nitric oxide synthase (eNOS), reduced generation and ...
Cited by 9 - Related articles - All 2 versions

Role of advanced glycation end products (AGEs) and oxidative stress in diabetic retinopathy


S Yamagishi, S Ueda, T Matsui, K Nakamura, … - Current pharmaceutical design, 2008 - ingentaconnect.com
Abstract: Diabetic retinopathy is a common and potentially devastating
microvascular complication in diabetes and is a leading cause of acquired
blindness among the people of occupational age. However, current ...
Cited by 11 - Related articles - BL Direct - All 3 versions

The role of protein kinase C activation in diabetic nephropathy


H Noh, GL King - Kidney International, 2007 - nature.com
Diabetic nephropathy is the leading cause of end-stage renal disease worldwide
and an independent risk factor for all-cause and cardiovascular mortalities in
diabetic patients. New insights into the molecular mechanisms that underlie ...
Cited by 11 - Related articles - BL Direct - All 2 versions

Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess …

- physiology.org [PDF] 
MG Rosca, TG Mustata, MT Kinter, AM … - American Journal of Physiology- Renal Physiology, 2005 - Am Physiological Soc
69 articles, 22 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/289/2/F420#BIBL ... 9 other
HighWire hosted articles, the first 5 are: This article has been cited by
Cited by 64 - Related articles - BL Direct - All 6 versions


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