JJ Meier, AE Butler, Y Saisho, T Monchamp, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Little is known about the capacity, mechanisms, or timing of growth
in β-cell mass in humans. We sought to establish if the predominant expansion
of β-cell mass in humans occurs in early childhood and if, as in rodents, ... Cited by 23 - Related articles - All 3 versions
- ►diabetesjournals.org HA Russ, Y Bar, P Ravassard, S Efrat - Diabetes, 2008 - Am Diabetes Assoc RESULTS— β-Cells were efficiently and specifically labeled by the dual virus
system. Label + , insulin − cells derived from β-cells were shown to
proliferate for a maximum of 16 population doublings, with an approximate ... Cited by 19 - Related articles - All 4 versions
PC Butler, JJ Meier, AE Butler, A Bhushan - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov Replication of beta cells is an important source of beta-cell expansion in early
childhood. The recent linkage of type 2 diabetes with several transcription
factors involved in cell cycle regulation implies that growth of the ... Cited by 41 - Related articles - BL Direct - All 3 versions
- ►pubget.com [PDF] AE Butler, R Galasso, JJ Meier, R Basu, RA … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Type 1 diabetes is characterised by a deficit in beta
cell mass thought to be due to immune- mediated increased beta cell apoptosis.
Beta cell turnover has not been examined in the context of new-onset type 1 ... Cited by 19 - Related articles - BL Direct - All 3 versions
LC Alonso, T Yokoe, P Zhang, DK Scott, SK … - Diabetes, 2007 - Am Diabetes Assoc Developing new techniques to induce β-cells to replicate is a major goal in
diabetes research. Endogenous β-cells replicate in response to metabolic
changes, such as obesity and pregnancy, which increase insulin requirement. ... Cited by 28 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org MM Rankin, JA Kushner - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE Regeneration of the insulin-secreting β-cells is a fundamental
research goal that could benefit patients with either type 1 or type 2 diabetes.
β-Cell proliferation can be acutely stimulated by a variety of stimuli in ... Cited by 6 - Related articles - All 3 versions
- ►slas.ac.cn [PDF] X Xu, J D'Hoker, G Stange, S Bonné, N De … - Cell, 2008 - Elsevier Novel strategies in diabetes therapy would obviously benefit from the use of
beta (β) cell stem/progenitor cells. However, whether or not adult β cell
progenitors exist is one of the most controversial issues in today's ... Cited by 99 - Related articles - All 9 versions
SK Karnik, H Chen, GW McLean, JJ Heit, X … - Science, 2007 - sciencemag.org A list of selected additional articles on the Science Web sites ... 4
article(s) on the ISI Web of Science. cited by This article has been ... :
subject collections This article appears in the following Cited by 55 - Related articles - BL Direct - All 8 versions
JJ Meier, AE Butler, R Galasso, RA Rizza, PC … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Type 1 and type 2 diabetes are charac- terised by a
beta cell deficit. Islet hyperplasia has been described in patients with
Zollinger–Ellison syndrome secondary to gastrin-producing tumours ... Cited by 21 - Related articles - BL Direct - All 5 versions
JJ Meier, A Bhushan, AE Butler, RA Rizza, PC … - Diabetologia, 2005 - Springer Abstract Aims/hypothesis: Type 1 diabetes is widely held to result from an
irreversible loss of insulin-secreting beta cells. However, insulin secretion is
detectable in some peo- ple with long-standing type 1 diabetes, indicating ... Cited by 103 - Related articles - BL Direct - All 5 versions
