AI Tarasov, TJ Nicolson, JP Riveline, TK … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— A mutation in ABCC8/SUR1, leading to a Y356C substitution in the
seventh membrane-spanning α-helix, was observed in a patient diagnosed with
hyperglycemia at age 39 years and in two adult offspring with impaired ... Cited by 1 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] AI Tarasov, T Nicolson, JP Riveline, TK … - Diabetes, 2008 - Am Diabetes Assoc Page 1. A rare mutation in ABCC8/SUR1 leading to altered K ATP channel activity
and β-cell glucose sensing is associated with type ... Cited by 1 - Related articles - All 2 versions
- ►nih.gov P Tammaro, SE Flanagan, B Zadek, S … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis Heterozygous activating mutations in the pancreatic
ATP-sensitive K+ channel cause permanent neonatal diabetes mellitus (PNDM). This
results from a decrease in the ability of ATP to close the channel, which ... Cited by 4 - Related articles - BL Direct - All 7 versions
Y Moriyama, M Hiasa, T Matsumoto, H Omote - Xenobiotica, 2008 - informahealthcare.com Upon absorption, drugs reach target cells, and then are excreted from the
kidneys and liver (Pritchard and Miller 1993) and during these processes the
drugs may pass through numerous cells via transporter-mediated pathways ... Cited by 6 - Related articles - All 8 versions
CM RIPSIN, J URBAN - MANAGEMENT - findlay.edu Evidence-based guidelines for the treatment of type 2 diabetes mellitus focus on
three areas: intensive lifestyle inter- vention that includes at least ISO
minutes per week of physical activity, weight loss with an initial goal of7 ... Cited by 5 - Related articles - View as HTML - All 5 versions
H Neeli, R Gadi, DJ Rader - Current Diabetes Reports, 2009 - Springer Cardiovascular disease is a significant cause of morbidity and mortality in
patients with diabetes mellitus. The lipid profile of type 2 diabetes melli- tus
is characterized by increased triglycerides (TGs), decreased high-density ... Cited by 5 - Related articles - All 2 versions
- ►diabetesjournals.org ML Becker, LE Visser, RHN van Schaik, A … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE— Metformin, an oral glucose-lowering drug, is taken up in
hepatocytes by the organic cation transporter (OCT) 1 and in renal epithelium by
OCT2. In these cells, the multidrug and toxin extrusion (MATE) 1 protein, ... Cited by 9 - Related articles - All 4 versions
DU Schulze, M Düfer, B Wieringa, P Krippeit … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis In a previous study, we demonstrated that a creatine
kinase (CK) modulates K ATP channel activity in pancreatic beta cells. To
explore phosphotransfer signalling pathways in more detail, we examined ... Cited by 8 - Related articles - BL Direct - All 6 versions
MI McCarthy, E Zeggini - Trends in Pharmacological Sciences, 2007 - Elsevier Type 2 diabetes is a complex, multifactorial disease, for which genetic and
environmental factors jointly determine susceptibility. Disentangling the
genetic aetiology of Type 2 diabetes has proven a challenging task, ... Cited by 10 - Related articles - All 3 versions
