- ►diabetesjournals.org RR Kapoor, J Locke, K Colclough, J Wales, JJ Conn, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Mutations in the human HNF4A gene encoding the hepatocyte nuclear factor
(HNF)-4α are known to cause maturity-onset diabetes of the young (MODY), which is characterized
by autosomal-dominant inheritance and impaired glucose-stimulated insulin secretion ... Cited by 8 - Related articles - All 3 versions
- ►fetalneonatal.com K Hussain, O Blankenstein, P De Lonlay, HT … - British Medical …, 2007 - adc.bmj.com Gary E Butler, Department of Paediatrics and Growth, Institute of Health Sciences, University
of Reading, Reading, UK Elaine A Beadle, Department of Philosophy, University of Reading,
Reading, UK ... Correspondence to: Professor Gary E Butler, Department of Paediatrics ... Cited by 7 - Related articles - BL Direct - All 5 versions
SE Pinney, C MacMullen, S Becker, YW … - The Journal of …, 2008 - pubmedcentral.nih.gov Congenital hyperinsulinism is a condition of dysregulated insulin secretion often caused by inactivating
mutations of the ATP-sensitive K + (K ATP ) channel in the pancreatic β cell. Though most
disease-causing mutations of the 2 genes encoding K ATP subunits, ABCC8 (SUR1) and ... Cited by 12 - Related articles - All 6 versions
RR Kapoor, C James, K Hussain - Nature Clinical Practice Endocrinology & …, 2009 - nature.com Dr Ritika Kapoor is a Clinical Research Fellow and Honorary Specialist Registrar at the Institute
of Child Health University College London and Great Ormond Street Hospital for Children National
Health Services Trust in London, UK. After completing her core training in general ... Cited by 3 - Related articles - All 3 versions
MD Hussain, K Hussain - Am Diabetes Assoc Persistent Hyperinsulinaemic Hypoglycaemia and Maturity Onset Diabetes of the Young
(MODY) due to Heterozygous HNF4A Mutations ... 1Ritika R Kapoor MRCPCH, 2Jonathan Locke
MBiol, 3Kevin Colclough BSc, 4Jerry Wales FRCP, 5Jennifer J Conn FRCP, 2Andrew T ... Related articles
SS Fajans, GI Bell - Diabetologia, 2007 - Springer To the Editor: In a recent publication, Pearson et al. [1] reported on a previously unrecognised
feature of the natural history of the type 1 form of maturity onset diabetes of the young
(MODY1), which is caused by mutations in the gene encoding hepatocyte nuclear factor ... Cited by 8 - Related articles - BL Direct - All 2 versions
L Damaj, M le Lorch, V Verkarre, C Werl, L … - Journal of Clinical …, 2008 - Endocrine Soc Context: Focal forms of congenital hyperinsulinism are due to a constitutional heterozygous mutation
of paternal origin in the ABCC8 gene, more often than the KCNJ11 gene, located in the
11p15.1 region. This mutation is associated with the loss of the maternally inherited ... Cited by 3 - Related articles - All 3 versions
K Hussain, SE Flanagan, VV Smith, M Ashworth, M Day … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE— Congenital hyperinsulinism (CHI) may be due to diffuse or focal pancreatic
disease. The diffuse form is associated with an increase in the size of β-cell nuclei throughout
the whole of the pancreas and most commonly results from recessive ATP-sensitive K + ... Cited by 10 - Related articles - BL Direct - All 4 versions
T Meissner, B Friedmann, JG Okun, MA … - Hormone and …, 2005 - 万方数据资源系统 Exercise-induced hyperinsulinism (EIHI) is a recently described entity characterised by recurrent
episodes of hypoglycaemia induced by physical exercise. The index patient for this disorder
and a matched control were subjected to aerobic and anaerobic exercise tests on a cycle ... Cited by 10 - Related articles - BL Direct - All 7 versions
- ►eje.org HBT Christesen, ND Tribble, A Molven, J Siddiqui, T … - European Journal of …, 2008 - eje.org Results: In five patients, four heterozygous GCK mutations (S64Y, T65I, W99R and A456V) were
identified, out of which S64Y was novel. Two of the mutations arose de novo, three were dominantly
inherited. All the five patients were medically responsive. In the combined Danish and ... Cited by 7 - Related articles - All 7 versions
