T Costacou, RE Ferrell, TJ Orchard - Diabetes, 2008 - Am Diabetes Assoc RESULTS—The proportions of the cohort with the haptoglobin 1/1, 2/1, and 2/2 genotypes were
11.5, 41.3, and 47.2%, respectively. During 18 years of follow-up, there were 135 (29.8%) incident
CAD events. Univariately, the proportion of CAD events increased from 15.4 to 28.3 and ... Cited by 11 - Related articles - All 4 versions
S Blum, U Milman, C Shapira, AP Levy - Pharmacogenomics, 2008 - Future Medicine The public health and economic burdens from diabetes mellitus (DM) are presently staggering
and are becoming more severe. Morbidity and mortality from DM is due to the effect of DM on
the cardiovascular system. Accelerated atherosclerosis and its sequalae are by far the ... Cited by 3 - Related articles - All 3 versions
- ►diabetesjournals.org R Asleh, S Blum, S Kalet-Litman, J Alshiek, R Miller- … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Pharmacogenomics is a key component of personalized medicine. The Israel
Cardiovascular Events Reduction with Vitamin E Study, a prospective placebo-controlled
study, recently demonstrated that vitamin E could dramatically reduce CVD in individuals ... Cited by 15 - Related articles - All 4 versions
RMLR Asleh, MHT Aviram, MLJE Yulish, BBS … - Circulation …, 2006 - Am Heart Assoc Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams & Wilkins, a division
of Wolters ... Haptoglobin Genotype Is a Regulator of Reverse Cholesterol Cited by 18 - Related articles - All 8 versions
[CITATION] Haptoglobin genotype is predictive of major adverse cardiac events in the one year …
- ►ahajournals.org AP Levy, K Purushothaman, NS Levy, M … - Circulation …, 2007 - Am Heart Assoc In individuals with diabetes mellitus (DM), the haptoglobin (Hp) genotype is a major determinant
of susceptibility to myocardial infarction. We have proposed that this is because of DM and Hp
genotype–dependent differences in the response to intraplaque hemorrhage. The ... Cited by 31 - Related articles - All 8 versions
M Suleiman, D Aronson, R Asleh, MR Kapeliovich, A … - Diabetes, 2005 - Am Diabetes Assoc Patients with diabetes presenting with acute myocardial infarction (AMI) have an increased rate
of death and heart failure. Patients with diabetes homozygous for the haptoglobin (Hp) 1 allele
(Hp 1-1) develop fewer vascular complications. We tested the hypothesis that Hp type is ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►nih.gov I Azarov, X He, A Jeffers, S Basu, B Ucer, RR Hantgan, … - Nitric Oxide, 2008 - Elsevier Cell-free hemoglobin, released from the red cell, may play a major role in regulating the bioavailability
of nitric oxide. The abundant serum protein haptoglobin, rapidly binds to free hemoglobin forming
a stable complex accelerating its clearance. The haptoglobin gene is polymorphic with ... Cited by 9 - Related articles - All 3 versions
AP Levy, HC Gerstein, R Miller-Lotan, R Ratner, M … - Diabetes Care, 2004 - Am Diabetes Assoc Hp type was measured in 3,167 participants (1,078 with diabetes) of the Heart Outcomes Prevention
Evaluation (HOPE) trial, which evaluated the 4.5-year effects of 400 IU vitamin E daily on the
primary composite of CV death, myocardial infarction, and stroke (1). No significant ... Cited by 33 - Related articles - BL Direct - All 5 versions
