- ►diabetesjournals.org DJ Smyth, JD Cooper, JMM Howson, NM Walker … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The disease association of the common 1858C>T Arg620Trp (rs2476601)
nonsynonymous single nucleotide polymorphism (SNP) of protein tyrosine
phosphatase; nonreceptor type 22 (PTPN22) on chromosome 1p13 has been ... Cited by 16 - Related articles - All 4 versions
LM Maier, DA Hafler - Nature Genetics, 2008 - nature.com The discovery of new risk variants for systemic lupus erythematosis (SLE),
particularly around lymphocyte signaling pathways and integrins involved in
clearing complement, provides fresh insights into this common human ... Cited by 7 - Related articles - BL Direct - All 2 versions
- ►nih.gov M Bjørnvold, DE Undlien, G Joner, K Dahl- … - Diabetologia, 2008 - Springer Abstract Background/hypothesis HLA, INS, PTPN22 and CTLA4 are considered to be
confirmed type 1 diabetes susceptibil- ity genes. HLA, PTPN22 and CTLA4 are
known to be involved in immune regulation. Few studies have system- Cited by 8 - Related articles - BL Direct - All 6 versions
AK Steck, SY Liu, K McFann, KJ Barriga, SR … - Pediatric Diabetes, 2006 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org HQ Qu, A Montpetit, B Ge, TJ Hudson, C … - Diabetes, 2007 - Am Diabetes Assoc A novel type 1 diabetes locus was mapped to the interleukin-2 receptor α gene
(IL2RA) on chromosome 10p15.1, encoding an important modulator of immunity. The
aim of the current study was to confirm the association of IL2RA with type ... Cited by 38 - Related articles - BL Direct - All 5 versions
AC Makis, E Galanakis, EC Hatzimichael, ZL … - Journal of Infection, 2005 - Elsevier Brucellosis is characterized by chronicity and relapses despite efficacious
treatment. Cytokines and especially the Th1/Th2 balance may be involved in the
susceptibility or resistance to the Brucella species. In order to identify ... Cited by 11 - Related articles - All 10 versions
WM Ridgway, LB Peterson, JA Todd, DB … - Advances in Immunology, 2008 - Elsevier Human genome wide association studies (GWAS) have recently identified at least
four new, non-MHC-linked candidate genes or gene regions causing type one
diabetes (T1D), highlighting the need for functional models to investigate ... Cited by 2 - Related articles - All 3 versions
A Barton, W Thomson, X Ke, S Eyre, A Hinks, … - Nature genetics, 2008 - nature.com The WTCCC study identified 49 SNPs putatively associated with rheumatoid
arthritis at P = 1 10 -4 - 1 10 -5 (tier 3). Here we show that three of these
SNPs, mapping to chromosome 10p15 (rs4750316), 12q13 (rs1678542) and 22q13 ( ... Cited by 25 - Related articles - All 4 versions
PL De Jager, S Sawcer, A Waliszewska, L … - European Journal of Human Genetics, 2005 - nature.com The 620W allele of PTPN22 has been associated with susceptibility to several
different forms of chronic inflammatory disease, including Type 1 diabetes
(T1D), rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and ... Cited by 15 - Related articles - BL Direct - All 6 versions
SV Ramagopalan, C Anderson, AD Sadovnick, … - New England Journal of Medicine, 2007 - content.nejm.org Marshall JWB, Cummings RM, Bowes LJ, Ridley RM, Green AR. Functional and
histological evidence for the protective ef- fect of NXY-059 in a primate model
of stroke when given 4 hours after occlusion. Stroke 2003;34:2228-33. ... Cited by 14 - Related articles - All 3 versions
