- ►diabetesjournals.org LW Harries, JM Locke, B Shields, NA Hanley, KP … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—HNF4A was expressed exclusively from the P2 promoter in adult pancreas, but from
9 weeks until at least 26 weeks after conception, up to 23% of expression in fetal pancreas was
of P1 origin. HNF4A4–6 transcripts were not detected in any tissue. In whole pancreas, ... Cited by 9 - Related articles - All 6 versions
LWH PhD, JML MBiol, BS PhD, NAH PhD, KPH PhD, … - Am Diabetes Assoc 1Institute of Biomedical and Clinical Sciences, Peninsula Medical School, Exeter, UK. 2Centre
for Human Development, Stem Cells & Regeneration; Human Genetics Division, University of
Southampton, Southampton, UK. 3Department of Clinical Medicine, University of Bergen, ... Related articles
LW Harries - Expert Review of Endocrinology and Metabolism, 2006 - ingentaconnect.com Variation in mRNA processing has the capacity to exert fine control over gene expression in
most cell types. The hepatic nuclear factor genes, like approximately 74% of the genome, produce
multiple transcripts. Hepatic nuclear factor isoforms exhibit both spatial and temporal ... Cited by 3 - Related articles - All 3 versions
S Sookoian, C Gemma, CJ Pirola - Molecular Genetics and Metabolism, 2009 - Elsevier Six haplotype blocks of LD were constructed with SNPs with r 2 > 0.8; there were also 14 unlinked
SNPs. Overall, we included 22,920 cases and 26.657 controls. Among 17 heterogeneous studies
(21,881 cases and 24,915 controls), including 3 SNPs of P2 promoter region in block 1, ... Related articles - All 2 versions
J Huang, LL Levitsky, DB Rhoads - Experimental Cell Research, 2009 - Elsevier Hepatocyte nuclear factor 4α (HNF4α) is a critical transcription factor for pancreas and liver development
and functions in islet β cells to maintain glucose homeostasis. Mutations in the human HNF4A
gene lead to maturity onset diabetes of the young (MODY1) and polymorphisms are ... Related articles - All 2 versions
EL Edghill, S Hameed, CF Verge, O Rubio- … - JOP. J Pancreas (Online …, 2009 - joplink.net Recessive mutations in the SLC29A3 gene have recently been shown to result in diabetes
[1, 2]. In the last year eleven families with the H syndrome (OMIM#612391) and five families with
pigmented hypertrichosis with insulin dependent diabetes (PHID) have been described, ... Related articles - Cached - All 3 versions
JM Locke, S Ellard, VF Norwood, LW Harries - Diabetic Medicine, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Related articles - All 3 versions
- ►diabetesjournals.org BZ Stanger - Diabetes, 2008 - Am Diabetes Assoc The first compelling evidence that intrauterine environment dictates later metabolic outcome
was the cohort study of Ravelli et al. (1) of 300,000 men conceived during the Dutch famine of
1944–1945. Embryos exposed to malnutrition during the first half of pregnancy, but not ... Related articles - All 2 versions
S Senkel, C Waldner, GU Ryffel, H Thomas - BMC Research Notes, 2009 - biomedcentral.com This Provisional PDF corresponds to the article as it appeared upon acceptance. Fully formatted
PDF and full text (HTML) versions will be made available soon. ... Improved conditional expression
systems resulting in physiological level of HNF4alpha expression confirm HNF4alpha ... Related articles - View as HTML - All 2 versions
- ►endocrinology-journals.org HJ Welters, S Senkel, L Klein-Hitpass, S … - Journal of …, 2006 - Soc Endocrinology Mutations in the gene encoding hepatocyte nuclear factor (HNF)1ß result in maturity-onset diabetes
of the young-(MODY)5, by impairing insulin secretory responses and, possibly, by reducing
ß-cell mass. The functional role of HNF1ß in normal ß-cells is poorly understood; ... Cited by 10 - Related articles - BL Direct - All 3 versions
