R Basu, V Chandramouli, B Dicke, BR Landau, RA … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Plasma C2 glucose and plasma 2 H 2 O enrichment were equal in both groups before
the clamp, resulting in equivalent estimates of gluconeogenesis and glycogenolysis. In
contrast, plasma C2 glucose and plasma C5 glucose enrichments fell throughout the ... Related articles - All 5 versions
JG Jones, A Fagulha, C Barosa, M Bastos, L Barros, C … - Diabetes, 2006 - Am Diabetes Assoc The contributions of hepatic glycogenolysis to fasting glucose production and direct pathway
to hepatic glycogen synthesis were quantified in eight type 1 diabetic patients and nine healthy
control subjects by ingestion of 2 H 2 O and acetaminophen before breakfast followed by ... Cited by 6 - Related articles - BL Direct - All 5 versions
R Basu, V Chandramouli, B Dicke, B Landau, R Rizza - Diabetes, 2005 - Am Diabetes Assoc To determine whether the hepatic insulin resistance of obesity and type 2 diabetes is due to impaired
insulin-induced suppression of glycogenolysis as well as gluconeogenesis, 10 lean
nondiabetic, 10 obese nondiabetic, and 11 obese type 2 diabetic subjects were studied ... Cited by 25 - Related articles - All 5 versions
R Basu, P Shah, A Basu, B Norby, B Dicke, V … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Glucose was clamped before and after therapy at ∼5 mmol/l, insulin raised to
∼180 pmol/l, C-peptide suppressed with somatostatin, glucagon replaced at ∼75 pg/ml, and
glycerol maintained at ∼200 mmol/l to ensure comparable and equal portal ... Cited by 10 - Related articles - BL Direct - All 8 versions
- ►physiology.org G Allick, SN van der Crabben, MT … - American Journal of …, 2006 - Am Physiological Soc Fasting gluconeogenesis (GNG) is often quantified using the 2 H 2 O technique, which is based
on plasma 2 H 2 O enrichment and ensuing enrichment of plasma glucose at the C5 and C2
positions. Fractional (fr)GNG can be calculated using the ratio of C5 to C2 enrichment or ... Cited by 4 - Related articles - BL Direct - All 3 versions
G Bock, E Chittilapilly, R Basu, G Toffolo, C Cobelli, V … - Am Diabetes Assoc Gerlies Bock, MD, Elizabeth Chittilapilly, MD, Rita Basu, MD, Gianna Toffolo, PhD, Claudio
Cobelli, PhD, Visvanathan Chandramouli, PhD, Bernard R. Landau, MD, PhD, and Robert A.
Rizza, MD ... Division of Endocrinology, Diabetes, Metabolism & Nutrition, Mayo Clinic ... Related articles
G Bock, E Chittilapilly, R Basu, G Toffolo, C Cobelli, V … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—Despite higher (P < 0.001) insulin and C-peptide concentrations and visceral fat
(P < 0.05), fasting EGP and glucose disposal did not differ between IFG and NFG subjects, implying
hepatic and extrahepatic insulin resistance. This was confirmed during preprandial ... Cited by 7 - Related articles - BL Direct - All 5 versions
G Bock, E Chittilapilly, R Basu, G Toffolo, C Cobelli, V … - DIABETES, 2007 - Am Diabetes Assoc P eople with impaired fasting glucose (IFG; fasting glucose 100–125 mg/dl) have an 30% chance
of developing diabetes over the next 10 years (1–3). Numerous studies have shown that IFG
is asso- ciated with defects in both insulin secretion and action that are particularly ... Related articles
- ►physiology.org [PDF] R Basu, WF Schwenk, RA Rizza - American Journal of Physiology …, 2004 - Am Physiological Soc Page 1. 1 Fasting Glucose Production and Disappearance Both Are Abnormal In People With
“Mild” As Well As “Severe” Type 2 Diabetes: Contribution of Alterations in Glycogenolysis and
Gluconeogenesis Rita Basu W. Frederick Schwenk Robert A Rizza ... Related articles
G Boden - Life sciences, 2003 - Elsevier Gluconeogenesis (GNG), ie, the formation of glucose from non-glucose precursors, provides
the glucose needed by the central nervous system during prolonged fasting and therefore is
essential for survival during starvation [12]. Excessive GNG, on the other hand, is ... Cited by 25 - Related articles - All 5 versions
