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Protective Role of Programmed Death 1 Ligand 1 (PD-L1) in Nonobese Diabetic Mice

- diabetesjournals.org
CJ Wang, FC Chou, CH Chu, JC Wu, SH Lin, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Coinhibitory signals mediated via programmed death 1 (PD-1) receptor
play a critical role in downregulating immune responses and in maintaining
peripheral tolerance. Programmed death 1 ligand 1 (PD-L1), the interacting ...
Cited by 6 - Related articles - All 5 versions

Protective Role of Programmed Death 1 Ligand 1 in Nonobese Diabetic Mice: The Paradox …


HK Sytwu - Am Diabetes Assoc
Chia-Jen Wang,1 Feng-Cheng Chou,1 Chi-Hong Chu,2 Jen-Chine Wu,1 Shih-Hua Lin,3
Deh-Ming ... 1Graduate Institute of Life Sciences, 2Department of Surgery,
3Department of Internal Medicine, 4Department of Medical Research, ...
Related articles

Immunopathogenic role of TH1 cells in autoimmune diabetes: evidence from a T1 and T2 …


JT Hung, JH Liao, YC Lin, HY Chang, SF Wu, … - Journal of Autoimmunity, 2005 - Elsevier
To improve the feasibility of in vivo monitoring of autoreactive T cells in the
diabetogenic process, we generated T1 and T2 doubly transgenic non-obese
diabetic (NOD) mice in which transgenic human CD90 (hCD90) is ...
Cited by 10 - Related articles - All 4 versions

Altered availability of PD-1/PD ligands is associated with the failure to control …


D Yadav, N Hill, H Yagita, M Azuma, N … - Cellular Immunology, 2009 - Elsevier
Costimulation via the PD-1 and B7-H1/B7-DC pathway regulates immunity. We
investigated whether the PD-1/PD-L pathway is impaired in autoimmune diabetes. A
progressive increase in the expression of PD-1 and B7-H1/B7-DC on T cells ...
Related articles - All 2 versions

PD-1/PD—Ls 对自身免疫病及慢性感染的影响及对 OLP 研究的启示


杜观环, 唐国瑶 - 临床口腔医学杂志, 2008 - cqvip.com
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[PDF] Functional studies of candidate genes contributing to Type 1 Diabetes in the NOD mouse


M Lundholm - umu.diva-portal.org
Type 1 Diabetes (T1D) is an autoimmune disorder caused by both genetic and
environmental factors. The non-obese diabetic (NOD) mouse is one of the best and
most commonly studied animal models for T1D. This mouse strain ...
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Transgenic Expression of Single-Chain Anti-CTLA-4 Fv on ß Cells Protects Nonobese …

- sinica.edu.tw [PDF] 
SJ Shieh, FC Chou, PN Yu, WC Lin, DM Chang … - The Journal of Immunology - Am Assoc Immnol
T cell-mediated immunodestruction of pancreatic ß cells is the key process
responsible for both the development of autoimmune diabetes and the induction of
rejection during islet transplantation. In this study, we investigate the ...
Related articles - All 2 versions

Transgenic Expression of Single-Chain Anti-CTLA-4 Fv on {beta} Cells Protects Nonobese …


SJ Shieh, FC Chou, PN Yu, WC Lin, DM Chang … - The Journal of Immunology, 2009 - Am Assoc Immnol
T cell-mediated immunodestruction of pancreatic β cells is the key process
responsible for both the development of autoimmune diabetes and the induction of
rejection during islet transplantation. In this study, we investigate the ...
Related articles - All 3 versions

Effects of multiple site implantation on islet transplantation


JH Juang, CH Kuo, BRS Hsu - Transplantation proceedings, 2002 - Elsevier
Islet transplantation has led to insulin-independence in humans with
insulin-dependent diabetes mellitus.[1] However, these grafts usually fail in a
few weeks or months; only a few have functioned successfully for more than ...
Cited by 7 - Related articles - All 5 versions

Nondepleting anti-CD4 and soluble interleukin-1 receptor prevent autoimmune destruction of …


M Drage, P Zaccone, JM Phillips, F Nicoletti … - Transplantation, 2002 - journals.lww.com
Transplantation. Wolters Kluwer Health Logo. All Issues. ...
Cited by 8 - Related articles - BL Direct - All 4 versions


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