- ►diabetesjournals.org D Mokhtari, JW Myers, N Welsh - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We observed that overexpression of wild-type MEKK-1, but not of a kinase dead
MEKK-1 mutant, resulted in potentiation of cytokine-induced JNK activation, inhibitor of B (I
B) degradation, and cell death. Downregulation of MEKK-1 in human islet cells provoked ... Cited by 2 - Related articles - All 4 versions
E Oetjen, R Blume, I Cierny, C Schlag, A Kutschenko, R … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Inappropriate insulin secretion and biosyn- thesis are hallmarks of
beta cell dysfunction and contribute to the progression from a prediabetic state to overt diabetes
mellitus. During the prediabetic state, beta cells are exposed to elevated levels of ... Cited by 5 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] D Mokhtari, JW Myers, N Welsh - Diabetes, 2008 - Am Diabetes Assoc Correspondence shall be addressed to: Nils Welsh, Dept. Of Medical Cell Biology, Uppsala
University, Biomedicum, PO Box 571, S-751 23, Uppsala, Sweden. Email: Nils.Welsh@mcb.uu
.se ... Received for publication 27 November 2007 and accepted in revised form 08 April ... Related articles - All 2 versions
A Barbu, N Welsh - Journal of Liposome Research, 2007 - informahealthcare.com Cationic lipid/DNA-complexes have been widely used as gene transfer vectors because they
are less toxic and immunogenic than viral vectors. The aim of the present study was to improve
and characterize lipofection of an insulin-producing cell line. We compared the ... Cited by 3 - Related articles - BL Direct - All 5 versions
[CITATION] Identification of two essential threonine residues in the catalytic domain of Mekk1. …
CD Cohen, MT Lindenmeyer, F Eichinger, A Hahn, … - PLoS ONE, 2008 - pubmedcentral.nih.gov We examined microdissected human renal tissue with or without DN using Affymetrix oligonucleotide
microarrays (HG-U133A) by standard Robust Multi-array Analysis (RMA). Subsequent gene
ontology analysis by Database for Annotation, Visualization and Integrated Discovery ( ... Cited by 4 - Related articles - All 6 versions
- ►endojournals.org N Wooten, VK Bakalov, S Hill, CA Bondy - Journal of Clinical …, 2008 - Endocrine Soc Results: Total body fat (35 ± 8 vs. 28 ± 8%, P < 0.0001), sc abdominal fat (183 vs. 100 ml, P =
0.001), and intraabdominal fat (50 vs. 33 ml, P < 0.0001) were significantly greater in untreated
girls. Fasting glucose and insulin were similar, but the response to oral glucose was ... Cited by 4 - Related articles - BL Direct - All 5 versions
[CITATION] Interleukin-1beta-induced rat pancreatic islet NO synthesis requires both the p38 …
- ►endojournals.org D Mokhtari, JW Myers, N Welsh - Endocrinology, 2008 - Endocrine Soc The aim of the present investigation was to characterize the role of the MAPK kinase kinase-1
(MEKK-1) in stress-induced cell death of insulin producing cells. We observed that transient overexpression
of the wild type MEKK-1 protein in the insulin-producing cell lines RIN-5AH and βTC-6 ... Cited by 4 - Related articles - BL Direct - All 3 versions
MJ Schoemaker, AJ Swerdlow, CD Higgins, AF … - Journal of Clinical …, 2008 - Endocrine Soc Context: Turner syndrome is characterized by complete or partial X chromosome
monosomy. It is associated with substantial morbidity, but mortality risks and causes of death
are not well described. ... Objectives: Our objective was to investigate mortality and ... Cited by 5 - Related articles - All 5 versions
