- ►diabetesjournals.org KM Picha, MR Cunningham, DJ Drucker, A … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—We have developed a novel platform for display and delivery of
bioactive peptides that links the biological properties of the peptide to the
pharmacokinetic properties of an antibody. Peptides engineered in the ... Cited by 3 - Related articles - All 5 versions
T O'Neil, KO'Neil, CRD Inc - Am Diabetes Assoc Kristen M. Picha, Ph.D., Mark R. Cunningham, BS, Daniel J. Drucker, MD#, Ashok
Mathur, BS, Tatiana Ort, Ph.D., Michael Scully, BS, Avery Soderman MS, Tracy
Spinka-Doms, BS, Vedrana Stojanovic-Susulic, Ph.D., Beth Ann Thomas, BS, ... Related articles
W Glaesner, R Micanovic, SR Tschang - US Patent App. 10/433,108, 2003 - Google Patents US 20040053370A1 (19) United States (12) Patent Application Publication (io>
Pub. NO.: US 2004/0053370 Al Glaesner et al. (43) Pub. Date: Mar. 18,2004 (54)
GLP-1 FUSION PROTEINS (76) Inventors: Wolfgang Glaesner, Indianapolis, IN ... Cited by 2 - Related articles - All 8 versions
[CITATION] Overview of the design of the phase 3 studies for the longacting human GLP-1 analogue …
H Block, J Kubicek, J Labahn, U Roth, F … - Protein Expression and Purification, 2007 - Elsevier We describe an efficient strategy to produce high-quality proteins by using a
single large IMAC chromatography column and enzymatic His-tag removal via the
TAGZyme system in pilot scale. Numerous quality assays demonstrated a high ... Cited by 3 - Related articles - All 3 versions
H Su, M He, H Li, Q Liu, J Wang, Y Wang, W … - PLoS One, 2008 - pubmedcentral.nih.gov C57BL/6J and db/db mice were treated daily with Boc5 for 4 weeks and a range of
pharmacologic parameters, including hemoglobin A1c, intraperitoneal glucose
tolerance, insulin tolerance, fasting insulin and leptin levels, food ... Cited by 3 - Related articles - All 6 versions
RG Tiessen, JP Castaigne, JF Dreyfus, M … - International journal of clinical pharmacology and …, 2008 - ncbi.nlm.nih.gov OBJECTIVE: The safety, tolerability, pharmacokinetics and preliminary
pharmacodynamics of single rising doses of a novel GLP-1 analog, CJC-1131, was
evaluated. METHODS: CJC-1131 was subcutaneously injected in 8 groups (1.5 - ... Cited by 3 - Related articles - All 2 versions
H Sandberg, D Lutkemeyer, S Kuprin, M … - Biotechnology and bioengineering, 2006 - interscience.wiley.com The proteolytic activities expressed by a Chinese hamster ovary (CHO) cell line
in the cultivation supernatant during the production of recombinant factor VIII
were mapped with a broad spectrum protease assay and a series of different ... Cited by 3 - Related articles - BL Direct - All 6 versions
NR Pinelli, R Cha, MB Brown, LA Jaber - Ann Pharmacother, 2008 - Harvey Whitney Books Type 2 diabetes mellitus results from insulin resistance and defective en-
dogenous insulin secretion.1 The United Kingdom Prospective Diabetes Study
demonstrated a progressive 4% annual de- cline in pancreatic β-cell ... Cited by 5 - Related articles - All 6 versions
