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Scholar Results 1 - 10 of about 101 related to Han: Extracellular high-mobility group box 1 acts as an innate immune mediator to enhance.... (0.14 sec) 

Extracellular high-mobility group box 1 acts as an innate immune mediator to …

- diabetesjournals.org
J Han, J Zhong, W Wei, Y Wang, Y Huang, P Yang, S … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—During autoimmunity, HMGB1 can be passively released from damaged pancreatic
β-cells and actively secreted by islet infiltrated immune cells. Extracellular HMGB1 is potent in
inducing NOD dendritic cell maturation and stimulating macrophage activation. Blockade ...
Cited by 2 - Related articles - All 4 versions

Extracellular HMGB1 acts as an innate immune-mediator to enhance autoimmune …

- diabetesjournals.org [PDF] 
J Han, J Zhong, W Wei, Y Wang, Y Huang, P Yang, S … - Diabetes, 2008 - Am Diabetes Assoc
Junyan Han, 1 Jinxin Zhong, 1* Wenzhong Wei, 1 Ying Wang, 1 Yafei Huang, 1 Ping Yang, 1
Sharad ... Purohit, 1 Zheng Dong, 2 Mong-Heng Wang, 3 Jin-Xiong She, 1 Feili Gong, 4 David
M Stern 5 and ... 1 Center for Biotechnology and Genomic Medicine, Department of ...
Cited by 2 - Related articles - All 2 versions

Pancreatic transcription factors and their role in the birth, life and survival of the …


AS Bernardo, CW Hay, K Docherty - Molecular and Cellular Endocrinology, 2008 - Elsevier
In recent years major progress has been made in understanding the role of transcription factors
in the development of the endocrine pancreas in the mouse. Here we describe how a number
of these transcription factors play a role in maintaining the differentiated phenotype of the ...
Cited by 4 - Related articles - All 3 versions

Innate immunity: cutaneous expression of Toll-like receptors


P Musette, AI Auquit, E Begon - Médecine sciences: M/S, 2006 - ncbi.nlm.nih.gov
Toll receptors were first identified as an essential molecule for embryonic patterning in Drosophila
and were subsequently shown to be a key in antibacterial and antifungal immunity in adult
flies. Toll receptors have been conserved throughout evolution. In mammals, TLRs have ...
Cited by 5 - Related articles

Heme oxygenase-1 upregulation significantly inhibits TNF-α and Hmgb1 releasing …


Q Gong, H Yin, M Fang, Y Xiang, C Yuan, GY … - International …, 2008 - Elsevier
The present study was designed to investigate whether administration of CoPPIX, an HO-1
inducer, could significantly inhibit TNF-α and Hmgb1 expression and thus attenuate the acute
lung injury (ALI) induced by lipopolysaccharide (LPS) in mice. Acute lung injury was ...
Cited by 9 - Related articles - All 3 versions

Cyclical and alternating infusions of glucose and intralipid in rats inhibit insulin …

- diabetesjournals.org
DK Hagman, MG Latour, SK Chakrabarti, G Fontes, J … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Prolonged exposure of isolated islets of Langerhans to elevated levels of fatty
acids, in the presence of high glucose, impairs insulin gene expression via a transcriptional mechanism
involving nuclear exclusion of pancreas-duodenum homeobox-1 (Pdx-1) and loss of ...
Cited by 5 - Related articles - BL Direct - All 4 versions

SREBPs: physiology and pathophysiology of the SREBP family


H Shimano - FEBS J, 2009 - interscience.wiley.com
Sterol regulatory element-binding proteins (SREBPs) have been established as physiological
regulators of lipid synthesis. The molecular mechanisms by which cellular sterol balance and
nutritional states regulate SREBP activities are the current research focus of this field. ...
Cited by 6 - Related articles - All 4 versions

Autophagy-independent incorporation of GFP-LC3 into protein aggregates is …


E Shvets, Z Elazar - Autophagy, 2008 - ncbi.nlm.nih.gov
LC3 is a widely used marker of autophagosomes in mammalian cells. However, in addition to
its autophagosomal localization, GFP-LC3 is often found associated with protein aggregates
that are formed in an autophagy-independent manner. In addition, LC3 directly interacts ...
Cited by 7 - Related articles - All 3 versions

[CITATION] The ParaHox Gene Cluster Is an Evolutionary Sister of the Hox Gene Cluster, 1998


NM Brooke, J Garcia-Fernandez, PW Holland - Nature
Cited by 2 - Related articles

[CITATION] Brü ning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR: Tissue specific …


RN Kulkarni - Cell, 1999
Cited by 2 - Related articles


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