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Scholar Results 1 - 10 of about 101 related to Gómez-Valadés: Pck1 gene silencing in the liver improves glycemia control, insulin sensitivity,.... (0.12 sec) 

Pck1 gene silencing in the liver improves glycemia control, insulin sensitivity, and …


AG Gómez-Valadés, A Méndez-Lucas, A Vidal-Alabró, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Treatment resulted in reduced PEPCK-C mRNA and protein. After treatment, improved
glycemia and insulinemia, lower triglyceride, and higher total and HDL cholesterol were
measured. Unsterified fatty acid accumulation was observed in the liver, in the absence of ...
Cited by 5 - Related articles - All 5 versions

Intense exercise induces the degradation of adenine nucleotide and purine …


T Mikami, J Kitagawa - European journal of applied physiology, 2006 - Springer
Abstract The purpose of this study was to investigate the influence of intense exercise on the
metabolism of ade- nine nucleotides in the liver. In the first experiment, to determine the degradation
of adenine nucleotides, he- patic adenine nucleotides of rats were labeled by an ...
Cited by 2 - Related articles - BL Direct - All 5 versions

Hepatic fat and adenosine triphosphate measurement in overweight and obese …


SF Solga, A Horska, S Hemker, S Crawford, C … - Liver …, 2008 - interscience.wiley.com
Methods: We measured hepatic fat and ATP using proton MRS ( 1 H MRS) and phosphorus MRS
( 31 P MRS) at baseline in adults enrolled in the Action for Health in Diabetes (Look AHEAD)
clinical trial at one site. Using logistic regression, we determined factors associated with ...
Cited by 4 - Related articles - BL Direct - All 3 versions

Glucagon response to exercise is critical for accelerated hepatic glutamine …

- physiology.org
MG Krishna, RH Coker, DB Lacy, BA … - American Journal of …, 2000 - Am Physiological Soc
The aim of this study was to determine the role of glucagon in hepatic glutamine (Gln) metabolism
during exercise. Sampling (artery, portal vein, and hepatic vein) and infusion (vena cava) catheters
and flow probes (portal vein, hepatic artery) were implanted in anesthetized dogs. At least ...
Cited by 5 - Related articles - BL Direct - All 3 versions

The glucagon receptor is required for the adaptive metabolic response to fasting

- cell.com
C Longuet, EM Sinclair, A Maida, LL Baggio, M Maziarz … - Cell metabolism, 2008 - Elsevier
Glucagon receptor (Gcgr) signaling maintains hepatic glucose production during the fasting
state; however, the importance of the Gcgr for lipid metabolism is unclear. We show here that
fasted Gcgr−/− mice exhibit a significant increase in hepatic triglyceride secretion and ...
Cited by 5 - Related articles - All 8 versions

[PDF] The promoter polymorphism-232C/G of thePCK1 gene is associated with type 2 …


SD Rees, AC Britten, S Bellary, JP O'Hare, S … - BMC Medical …, 2009 - biomedcentral.com
Simon D Rees (sdrees@bham.ac.uk) Abigail C Britten (acbritten@bham.ac.uk) Srikanth Bellary
(sribell@hotmail.com) J PAUL O'Hare (JPO-Hare@warwick.ac.uk) Sudhesh Kumar
(sudhesh.kumar@warwick.ac.uk) Anthony H Barnett (anthony.barnett@heartofengland. ...
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[PDF] NOVEL INSIGHTS INTO METABOLIC REGULATION BY GLUCAGON RECEPTOR …


E Berglund - 2009 - etd.library.vanderbilt.edu
Page 1. NOVEL INSIGHTS INTO METABOLIC REGULATION BY GLUCAGON RECEPTOR
ACTIVATION – INDUCTION OF HEPATIC ENERGY-DEPLETION AND AMPK SIGNALING
By Eric Berglund Dissertation Submitted to the Faculty of the ...
Related articles - View as HTML - All 2 versions

Hepatic energy state is regulated by glucagon receptor signaling in mice


ED Berglund, RS Lee-Young, DG Lustig, SE Lynes, EP … - 2009 - pubmedcentral.nih.gov
The hepatic energy state, defined by adenine nucleotide levels, couples metabolic pathways
with energy requirements. This coupling is fundamental in the adaptive response to many conditions
and is impaired in metabolic disease. We have found that the hepatic energy state is ...
Related articles - All 5 versions

Cytosolic phosphoenolpyruvate carboxykinase does not solely control the rate of …

- nih.gov
SC Burgess, TT He, Z Yan, J Lindner, AD Sherry, CR … - Cell metabolism, 2007 - Elsevier
When dietary carbohydrate is unavailable, glucose required to support metabolism in vital tissues
is generated via gluconeogenesis in the liver. Expression of phosphoenolpyruvate carboxykinase
(PEPCK), commonly considered the control point for liver gluconeogenesis, is normally ...
Cited by 14 - Related articles - All 11 versions

Effects of physical exercise on liver ATP levels in fasted and phosphate-injected …


A Ghanbari-Niaki, R Bergeron, MG … - … of physiology and …, 1999 - informahealthcare.com
A reduction in liver ATP concentration has been recently reported to provide a signal initiating
eating behavior in rats (Rawson et al., 1994a, b). These authors used the fructose analogue
2,5-anhydro-D- mannitol (2,5-AM) to trap hepatic phosphate and decrease ATP levels. ...
Cited by 7 - Related articles - BL Direct - All 6 versions


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