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Scholar Results 1 - 10 of about 101 related to Chang: Common variation in the fat mass and obesity-associated (FTO) gene confers risk of.... (0.13 sec) 

Common variation in the fat mass and obesity-associated (FTO) gene confers risk …

- diabetesjournals.org
YC Chang, PH Liu, WJ Lee, TJ Chang, YD Jiang, HY Li … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS— Among the 19 SNPs, the rs9939609 A allele was strongly associated with obesity
(P = 7.0 x 10 –4 ) and BMI (P = 0.0024) in the Chinese population. The odds ratio for obesity
was 2.60 (95% CI 1.24–5.46) (P = 0.011) for the AA genotype and 1.32 (1.05–1.66) (P = ...
Cited by 21 - Related articles - All 4 versions

FTO variants are associated with obesity in the Chinese and Malay populations in …

- diabetesjournals.org [PDF] 
JT Tan, R Dorajoo, M Seielstad, XL Sim, RTH Ong, KS … - Diabetes, 2008 - Am Diabetes Assoc
Arecent genome-wide association study for type 2 diabetes using a UK-based population re-
vealed a novel locus associated with BMI: the fat mass– and obesity-related gene (FTO) on chromosome
16 (1). The representative single-nucleotide polymorphism (SNP), rs9939609, was ...
Cited by 17 - Related articles - All 5 versions

Replication of genetic effects of FTO polymorphisms on BMI in a Korean population


SW Cha, SM Choi, KS Kim, BL Park, JR Kim, JY Kim, … - 2008 - nature.com
It has been newly reported in recent studies that single-nucleotide polymorphisms (SNPs) in
the first intron of the FTO gene have been associated with BMI in whites. To determine whether
the gene is associated with BMI in Asians also, we performed a replication study of the ...
Cited by 13 - Related articles - All 4 versions

Variations in the FTO gene are associated with severe obesity in the Japanese

- nih.gov
K Hotta, Y Nakata, T Matsuo, S Kamohara, K Kotani … - Journal of human …, 2008 - Springer
Abstract Variations in the fat-mass and obesity-associated gene (FTO) are associated with the
obesity phenotype in many Caucasian populations. This association with the obesity phenotype
is not clear in the Japanese. To investigate the relationship between the FTO gene and ...
Cited by 29 - Related articles - BL Direct - All 7 versions

Association analysis of the FTO gene with obesity in children of Caucasian and …


SFA Grant, M Li, JP Bradfield, CE Kim, K Annaiah, E … - PLos One, 2008 - pubmedcentral.nih.gov
Recently an association was demonstrated between the single nucleotide polymorphism
(SNP), rs9939609, within the FTO locus and obesity as a consequence of a genome wide association
(GWA) study of type 2 diabetes in adults. We examined the effects of two perfect ...
Cited by 21 - Related articles - All 6 versions

Common variation in the FTO gene confers risk of obesity and modulates body …

- diabetesjournals.org [PDF] 
YC Chang, PH Liu, WJ Lee, TJ Chang, YD Jiang, HY Li … - Diabetes, 2008 - Am Diabetes Assoc
Yi-Cheng Chang 1 , Pi-Hua Liu 2 , Wei-Jei Lee 3 , Tien-Jun Chang 4 , Yi-Der Jiang 4 ,
Hung-Yuan Li 4 , ... Shan-Shan Kuo 4 , Kuang-Chin Lee 4 , Lee-Ming Chuang 4,5 ... 1 Department
of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin,
Cited by 11 - Related articles - All 2 versions

Fat Mass–and Obesity-Associated (FTO) Gene Variant Is Associated With Obesity


L Qi, K Kang, C Zhang, RM van Dam, P Kraft, D Hunter, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We observed a trend toward decreasing associations between rs9939609 and BMI
at older age (≥65 years) in men, whereas the associations were constant across different age
groups in women. In addition, the single nucleotide polymorphism (SNP) rs9939609 was ...
Cited by 12 - Related articles - All 3 versions

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and …


A Haupt, C Thamer, J Machann, K Kirchhoff, N Stefan, … - Obesity, 2008 - nature.com
Polymorphisms in the fat mass- and obesity-associated (FTO) gene have been identified to be
associated with obesity and diabetes in large genome-wide association studies. We hypothesized
that variation in the FTO gene has an impact on whole body fat distribution and insulin ...
Cited by 16 - Related articles - All 4 versions

Association of the FTO gene with BMI


SC Hunt, S Stone, Y Xin, CA Scherer, CL Magness, SP … - Obesity, 2008 - nature.com
Variants in the FTO gene have been strongly associated with obesity in a very large sample
(38,759) of diabetic and control subjects. To replicate these findings, the previously reported
SNP in the FTO gene (rs9939609, T/A) was genotyped in 5,607 subjects from five ...
Cited by 24 - Related articles - All 3 versions

The FTO gene and measured food intake in children


J Wardle, C Llewellyn, S Sanderson, R Plomin - International Journal of …, 2008 - nature.com
Participants were 131 children aged 4–5 years, taking part in a behavioural study of food intake
for whom DNA was available for genotyping. The phenotypic indicator of intake was the child's
consumption of palatable food presented after having eaten a meal. We also assessed ...
Cited by 18 - Related articles - All 3 versions


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