- ►nih.gov P Monti, M Scirpoli, P Maffi, L Piemonti, A … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—Rapamycin is an immunosuppressive drug currently used to prevent
graft rejection in humans, which is considered permissive for tolerance
induction. Rapamycin allows expansion of both murine and human naturally ... Cited by 9 - Related articles - All 5 versions
JM Lawson, J Tremble, C Dayan, H Beyan, … - Clinical &# 38; Experimental Immunology, 2008 - ingentaconnect.com Type I diabetes (T1D) is a T cell-mediated autoimmune disease characterized by
loss of tolerance to islet autoantigens, leading to the destruction of
insulin-producing beta cells. Peripheral tolerance to self is maintained in ... Cited by 4 - Related articles - All 2 versions
RWG Gruessner, DER Sutherland, AC … - JAMA, 2005 - Am Med Assoc To the Editor: We would like to raise concerns about 3 possible flaws in the
design and analysis of the study by Dr Venstrom and colleagues. 1 First,
patients listed for a pancreas transplant at multiple centers, as well as ... Cited by 6 - Related articles - All 4 versions
M Guillot-Delost, M Cheraï, Y Hamel, M … - Journal of Gene Medicine, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 6 - Related articles - All 6 versions
N Gagliani, A Ferraro, MG Roncarolo, M … - Immunology Letters, 2009 - Elsevier Regulatory T cells (Tregs) are thought to be pivotal in controlling both
autoimmune and allogeneic undesired immune responses. Recently, an extensive
effort has been devoted to design clinical trials with Tregs in T ... Related articles - All 2 versions
G Jiang, Y Cui, X Zhong, S Tai, W Liu, Z Wang … - Archives of medical research, 2009 - Elsevier Type 1 diabetes (T1D) is an autoimmune disorder that results in destruction of
insulin-releasing β-cells of the pancreas. During the pathogenesis of T1D, at
least two phases of β-cell death occur: an initiation event wherein ... Related articles - All 8 versions
[CITATION] The authors review islet transplant outcomes and immunosuppression, and in particular the …
P Fiorina, AMJ Shapiro, C Ricordi, A Secchi - American Journal of Transplantation, 2008 - Blackwell Publishing Inc Related articles
M Donia, K Mangano, A Amoroso, MC Mazzarino … - Journal of Autoimmunity, 2009 - Elsevier We have presently evaluated the effects of the immunomodulatory drug rapamycin
on the course of protracted relapsing experimental allergic encephalomyelitis
(PR-EAE) in Dark Agouti (DA) rats, which serves as a preclinical model of ... Related articles - All 2 versions
J Yuen-Shan Tsang, Y Tanriver, S Jiang, E … - Transplant Immunology, 2009 - Elsevier CD4 + CD25 + regulatory T cells (Tregs) play a crucial role in controlling
immune responses. It is an appealing strategy to harness Tregs for adoptive cell
therapy to induce tolerance to allografts. Several approaches have been ... Related articles - All 2 versions
