- ►diabetesjournals.org V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps:
defective immunological tolerance, priming of anti-islet autoimmunity, and
destruction of insulin-producing β-cells. A number of genetic loci ... Cited by 4 - Related articles - All 5 versions
- ►diabetesjournals.org [PDF] V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc Page 1. Genetic determinants of Type 1 DM progression Impact of diabetes
susceptibility loci on progression from pre-diabetes to ... Related articles - All 2 versions
SA Hinke - Current opinion in molecular therapeutics, 2008 - ncbi.nlm.nih.gov Diamyd Medical AB is developing Diamyd (GAD-65), an alum formulation of a
full-length recombinant human glutamic acid decarboxylase 65 for subcutaneous
injection, for the potential prevention and treatment of type 1 diabetes ... Cited by 1 - Related articles - All 3 versions
A Nair, TR Wolter, AJ Meyers, D Zipris - System, 1927 - interscience.wiley.com We recently hypothesized that Toll-like receptor-induced innate upregulation by
Kilham rat virus (KRV) in the BioBreeding diabetes-resistant (BBDR) rat model
plays a key role in the mechanism of diabetes induction. To address this ... Cited by 2 - Related articles - All 4 versions
- ►adisonline.com [PDF] M von Herrath, D Rottembourg, D Bresson - BioDrugs, 2006 - ingentaconnect.com Page 1. Biodrugs 2006; 20 (6): 341-350 N OVEL T HERAPEUTIC S TRATEGIES
1173-8804/06/0006-0341/$39.95/0 2006 Adis Data Information BV. All rights reserved. ... Cited by 2 - Related articles - BL Direct - All 4 versions
SA Long, MR Walker, M Rieck, E James, WW … - European journal of immunology, 2009 - pubmedcentral.nih.gov CD4 + CD25 + FOXP3 + Treg cells require TCR engagement for suppressive function,
thus ensuring that suppression only occurs in the presence of specific antigens,
however, to date no studies have addressed the function of self ... Cited by 4 - Related articles - All 3 versions
SL Thrower, L James, W Hall, KM Green, S … - Clinical & Experimental Immunology, 2009 - interscience.wiley.com Immunotherapeutic strategies under consideration for type 1 diabetes include
modification of the autoimmune response through antigen-specific routes.
Administration of short peptides representing T cell epitopes targeted by ... Cited by 4 - Related articles - All 4 versions
KG GADKAR, LK Shoda, HT Kreuwel, S … - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2007 - interscience.wiley.com Abstract : Several publications describing the use of anti-CD40L monoclonal
antibodies (anti-CD40L) for the treatment of type 1 diabetes in non-obese
diabetic (NOD) mice have reported different treatment responses to similar ... Cited by 2 - Related articles - BL Direct - All 6 versions
- ►jimmunol.org E Enee, E Martinuzzi, P Blancou, JM Bach, R … - The Journal of Immunology, 2008 - Am Assoc Immnol CD8 + T cells play an important role in the initiation of insulitis and in the
destructive stage leading to insulin-dependent diabetes mellitus. A string of
recent studies has led to the identification of numerous HLA-A2-restricted ... Cited by 2 - Related articles - All 3 versions
X Wang, Z He, S Ghosh - Mathematical biosciences, 2006 - Elsevier The heterogeneity between young- and adult-onset type 1 diabetes (T1D) is well
known, but not well understood. We approach this question through mathematical
formulation and analysis of the dynamic interactions between the immune ... Cited by 2 - Related articles - All 4 versions
