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Scholar Results 1 - 10 of about 101 related to Huang: Plasmacytoid precursor dendritic cells from NOD mice exhibit impaired function: are.... (0.08 sec) 

Plasmacytoid precursor dendritic cells from NOD mice exhibit impaired function: …

- diabetesjournals.org
Y Huang, IJ Fugier-Vivier, T Miller, MJ Elliott, H Xu, LD … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—We report for the first time that NOD FCs are functionally impaired. They fail to facilitate
engraftment of syngeneic and allogeneic HSCs in vivo and do not enhance HSC clonogenicity
in vitro. NOD FCs contain subpopulations similar to those previously described in B6 FCs, ...
Cited by 2 - Related articles - All 5 versions

Interferon-α initiates type 1 diabetes in nonobese diabetic mice


Q Li, B Xu, SA Michie, KH Rubins, RD … - Proceedings of the …, 2008 - National Acad Sciences
With the goal of identifying changes in gene expression in CD4 + T cells during the development
of diabetes in the nonobese diabetic (NOD) mouse, we used DNA microarrays to analyze gene
expression in CD4 + T cells from the pancreatic draining lymph nodes of NOD/BDC 2.5 T ...
Cited by 4 - Related articles - All 6 versions

β-cell transplantation for diabetes therapy


C Ricordi, BJ Hering, AMJ Shapiro - The Lancet, 2008 - Elsevier
Islet transplantation outcomes are likely to improve substantially over the next 3–5 years, as a
result of novel immunosuppressive regimens with fewer toxic effects. Even more far-reaching
improvements will emerge from islet processing, alternative islet sources, cellular ...
Cited by 3 - Related articles - All 9 versions

Differential contributions of APC subsets to T cell activation in nonobese diabetic …

- jimmunol.org
AM Marleau, KL Summers, B Singh - The Journal of Immunology, 2008 - Am Assoc Immnol
Despite the pivotal role of dendritic cells (DC) in shaping immunity, little is known about their
functionality in type 1 diabetes. Moreover, due to the paucity of DC in vivo, functional studies
have relied largely upon in vitro-expanded cells to elucidate type 1 diabetes-associated ...
Cited by 4 - Related articles - All 2 versions

Resetting the functional capacity of regulatory T cells: a novel immunotherapeutic …


L Chatenoud, JF Bach - Expert Opin. Biol. Ther., 2005 - informahealthcare.com
Over the last few years, there has been a re-emergence of the concept of suppressor/regulatory
T cells among the central players of immune mecha- nisms controlling a wide variety of immune
responses from physiological autoreactivity (ie, response to self-antigens) to responses to ...
Cited by 4 - Related articles - All 4 versions

Plasmacytoid dendritic cells are proportionally expanded at diagnosis of type 1 …


JS Allen, K Pang, A Skowera, R Ellis, C Rackham, B … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—The balance of blood dendritic cells was profoundly disturbed at diabetes
diagnosis, with a significantly elevated proportion of plasmacytoid and reduction of myeloid cells
compared with control subjects. Dendritic cell subset distribution was normal in long- ...
Cited by 6 - Related articles - All 3 versions

Constitutive expression of B7-1 on B cells uncovers autoimmunity toward the B cell …

- jimmunol.org
H Bour-Jordan, BL Salomon, HL Thompson, … - The Journal of …, 2007 - Am Assoc Immnol
The NOD mouse is an invaluable model for the study of autoimmune diabetes. Furthermore,
although less appreciated, NOD mice are susceptible to other autoimmune diseases that can
be differentially manifested by altering the balance of T cell costimulatory pathways. In ...
Cited by 6 - Related articles - All 6 versions

[CITATION] Efficacy of regulatory T-cell immunotherapy: are inflammatory cytokines key …


J Bayry, S Lacroix-Desmazes, S Dasgupta, … - Nature reviews. …, 2008 - ncbi.nlm.nih.gov
1: Nat Rev Immunol. 2008 Jan;8(1):1p following 86; author reply 1p following 86.
Comment on: Nat Rev Immunol. 2007 Aug;7(8):585-98. Efficacy of regulatory T-cell
immunotherapy: are inflammatory cytokines key determinants? ...
Cited by 6 - Related articles - BL Direct - All 3 versions

The effector T cells of diabetic subjects are resistant to regulation via CD4+ …

- jimmunol.org
A Schneider, M Rieck, S Sanda, C Pihoker, C … - The Journal of …, 2008 - Am Assoc Immnol
Defects in immune regulation have been implicated in the pathogenesis of diabetes in mouse
and in man. In vitro assays using autologous regulatory (Treg) and responder effector (Teff) T
cells have shown that suppression is impaired in diabetic subjects. In this study, we ...
Cited by 9 - Related articles - All 2 versions

[CITATION] Induction of FoxP3 CD4 25 regulatory T cells following hemopoietic stem cell …


KN Taylor, VR Shinde-Patil, E Cohick… - J Immunol, 2007
Cited by 3 - Related articles


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