- ►nih.gov Y Bar, HA Russ, S Knoller, L Ouziel-Yahalom, … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—In vitro expansion of β-cells from adult human islets could solve
the tissue shortage for cell replacement therapy of diabetes. Culture of human
islet cells typically results in <16 cell doublings and loss of insulin ... Cited by 3 - Related articles - All 4 versions
Z Wang, Y Li, D Kong, S Banerjee, A Ahmad, … - Cancer research, 2009 - AACR Pancreatic cancer (PC) is a highly aggressive malignant disease, which is ranked
as the fourth leading cause of cancer-related deaths in the United States, with
37,000 newly diagnosed cases and 34,000 deaths per year in the United ... Cited by 3 - Related articles - All 4 versions
GV Shah, A Muralidharan, M Gokulgandhi, K … - Journal of Biological Chemistry, 2009 - ASBMB Calcitonin, a neuroendocrine peptide, and its receptor are localized in the
basal epithelium of benign prostate but in the secretory epithelium of malignant
prostates. The abundance of calcitonin and calcitonin receptor mRNA ... Cited by 3 - Related articles - All 3 versions
A Voulgari, A Pintzas - BBA-Reviews on Cancer, 2009 - Elsevier Epithelial–mesenchymal transition (EMT) is a key step during embryogenesis.
Accumulating evidence suggests a critical role in cancer progression, through
which tissue epithelial cancers invade and metastasise. Cell ... Cited by 5 - Related articles - All 2 versions
- ►diabetesjournals.org HA Russ, Y Bar, P Ravassard, S Efrat - Diabetes, 2008 - Am Diabetes Assoc RESULTS— β-Cells were efficiently and specifically labeled by the dual virus
system. Label + , insulin − cells derived from β-cells were shown to
proliferate for a maximum of 16 population doublings, with an approximate ... Cited by 19 - Related articles - All 4 versions
R Gallo, F Gambelli, B Gava, F Sasdelli, V … - Cell Death & Differentiation, 2007 - nature.com Cellular models and culture conditions for in vitro expansion of
insulin-producing cells represent a key element to develop cell therapy for
diabetes. Initial evidence that human -cells could be expanded after ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org DA Cano, IC Rulifson, PW Heiser, LB Swigart … - Diabetes, 2008 - Am Diabetes Assoc Several studies have shown that the adult pancreas possesses a limited potential
for β-cell regeneration upon tissue injury. One of the difficulties in studying
β-cell regeneration has been the lack of a robust, synchronized animal ... Cited by 15 - Related articles - BL Direct - All 3 versions
- ►biologists.org L Ulianich, C Garbi, AS Treglia, D Punzi, C … - Journal of Cell Science, 2008 - jcs.biologists.org Conditions perturbing the homeostasis of the endoplasmic reticulum (ER) cause
accumulation of unfolded proteins and trigger ER stress. In PC Cl3 thyroid
cells, thapsigargin and tunicamycin interfered with the folding of ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►nih.gov RA Morton, E Geras-Raaka, LM Wilson, BM … - Molecular and cellular endocrinology, 2007 - Elsevier We previously presented evidence that proliferative human islet precursor cells
may be derived in vitro from adult islets by epithelial-to-mesenchymal
transition (EMT) and show here that similar fibroblast-like cells can be ... Cited by 28 - Related articles - All 5 versions
- ►diabetesjournals.org F Atouf, CH Park, K Pechhold, M Ta, Y Choi, … - Diabetes, 2007 - Am Diabetes Assoc We used cre/loxP-based genetic lineage tracing analysis to test a previously
proposed hypothesis that in vitro cultured adult pancreatic β-cells undergo
epithelial-mesenchymal transition (EMT) to generate a highly proliferative, ... Cited by 30 - Related articles - BL Direct - All 5 versions
