- ►diabetesjournals.org G Boden, X Duan, C Homko, EJ Molina, WW … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Proteomic analysis revealed 19 differentially upregulated proteins in
fat of obese subjects. Three of these proteins were the ER stress–related
unfolded protein response (UPR) proteins calreticulin, protein disulfide- ... Cited by 23 - Related articles - All 5 versions
- ►endojournals.org NK Sharma, SK Das, AK Mondal, OG Hackney, … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Results: Adipocyte expression of most markers of ER stress, including chaperones
downstream of activating transcription factor 6, were significantly correlated
with BMI and percent fat (r > 0.5; P < 0.00001). Phosphorylation of ... Cited by 11 - Related articles - All 4 versions
- ►diabetesjournals.org MF Gregor, L Yang, E Fabbrini, BS Mohammed, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Subjects lost 39 ± 9% body wt at 1 year after GBP surgery (P <
0.001), which was associated with a marked improvement in hepatic, skeletal
muscle, and adipose tissue insulin sensitivity. Markers of ER stress in ... Cited by 9 - Related articles - All 4 versions
- ►physiology.org SK Das, WS Chu, AK Mondal, NK Sharma, PA … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Obesity and elevated cytokine secretion result in a chronic inflammatory state
and may cause the insulin resistance observed in type 2 diabetes. Recent studies
suggest a key role for endoplasmic reticulum stress in hepatocytes and ... Cited by 4 - Related articles - All 5 versions
T Hosoi, M Sasaki, T Miyahara, C Hashimoto, … - Molecular pharmacology, 2008 - ASPET Leptin is an important circulating signal for inhibiting food intake and body
weight gain. In recent years, "leptin resistance" has been considered to be one
of the main causes of obesity. However, the detailed mechanisms of leptin ... Cited by 6 - Related articles - All 3 versions
- ►jlr.org MF Gregor, GS Hotamisligil - The Journal of Lipid Research, 2007 - ASBMB In the context of obesity and its related maladies, the adipocyte plays a
central role in the balance, or imbalance, of metabolic homeostasis. An obese,
hypertrophic adipocyte is challenged by many insults, including surplus ... Cited by 78 - Related articles - All 5 versions
QG Zhou, M Zhou, FF Hou, X Peng - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc Protein energy wasting, a state of decreased stores of body protein and fat, is
a risk factor for mortality in advanced chronic kidney disease (CKD). Little is
known about the mechanism underlying loss of fat in CKD. Accumulation of ... Cited by 1 - Related articles - All 3 versions
M Bluher, N Bashan, I Shai, I Harman-Boehm, T … - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc Results: The amount of phosphorylated forms of the kinases provided evidence for
an activated stress-sensing pathway consisting of the MAP3K Ask1 (but not MLK3
or Tak1), and the MAP2Ks MKK4, 3/6, (but not MKK7), specifically in OM. OM ... Cited by 1 - Related articles - All 7 versions
- ►pnas.org E Bobrovnikova-Marjon, G Hatzivassiliou, C … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences The role of the endoplasmic reticulum stress-regulated kinase, PERK, in mammary
gland function was assessed through generation of a targeted deletion in mammary
epithelium. Characterization revealed that PERK is required for functional ... Cited by 4 - Related articles - All 5 versions
Y Wei, D Wang, MJ Pagliassotti - Molecular and Cellular Biochemistry, 2007 - Springer Abstract Lipid accumulation in non-adipose tissues leads to cell dysfunction and
apoptosis, a phenomenon known as lipotoxicity. Recent evidence suggests that
lipotoxicity in hepatocytes involves endoplasmic reticulum (ER) stress and ... Cited by 19 - Related articles - BL Direct - All 3 versions
