TG Deering, T Ogihara, AP Trace, B Maier, RG … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Within the pancreas, Set7/9 protein shows striking specificity for
islet cells, including α- and β-cells, as well as occasional cells within
ducts. Consistent with these findings, the Set7/9 gene promoter contained ... Cited by 7 - Related articles - All 3 versions
DR Cavener - Diabetes, 2009 - Am Diabetes Assoc In all cell types of the body, save one, the insulin gene is quiescent and is
ensconced in a compact and protected environment of chromatin. How the insulin
gene is coaxed out of its chromatin slumber in the pancreatic β-cell is ... Cited by 1 - Related articles - All 4 versions
P Jahanshahi, R Wu, JD Carter, CS … - Endocrinology, 2009 - Endocrine Soc Pulsatility is a fundamental feature of pancreatic islets and a hallmark of
hormone secretion. Isolated pancreatic islets endogenously generate rhythms in
secretion, metabolic activity, and intracellular calcium ([Ca 2+ ] i ) that ... Cited by 2 - Related articles - All 4 versions
F Miao, DD Smith, L Zhang, A Min, W Feng, R … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—A subset of genes in the type 1 diabetic cohort showed significant
increase in H3K9me2 in lymphocytes but not in monocytes. CLTA4, a type 1
diabetes susceptibility gene, was one of the candidates displaying ... Cited by 3 - Related articles - All 4 versions
Y Li, MA Reddy, F Miao, N Shanmugam, JK … - Journal of Biological Chemistry, 2008 - ASBMB Nuclear factor κ-B (NF-κB)-regulated inflammatory genes, such as TNF-α (tumor
necrosis factor-α), play key roles in the pathogenesis of inflammatory
diseases, including diabetes and the metabolic syndrome. However, the ... Cited by 6 - Related articles - All 4 versions
- ►pitt.edu [PDF] S Burke, 2009 - etd.library.pitt.edu Page 1. REGULATION OF THE L-TYPE PYRUVATE KINASE GENE BY GLUCOSE AND cAMP IN
ISLET β CELLS by Susan Burke BSc, University College Cork, 2004 ... Related articles - View as HTML - All 3 versions
AJ MacFarlane, A Strom, FW Scott - Mammalian Genome - Springer Abstract Type 1 diabetes (T1D) is an autoimmune dis- ease that has increased
two- to threefold over the past half century by as yet unknown means. It is
generally accepted that T1D is the result of gene–environment ... Related articles - All 2 versions
T Ueda, T Furusawa, T Kurahashi, L … - Molecular and Cellular Biology, 2009 - Am Soc Microbiol Improper glucose-stimulated insulin secretion from pancreatic β cells is a
major factor in the onset of type 2 diabetes. We now report that HMGN3, a
nuclear protein that binds to nucleosomes and affects chromatin function, ... Related articles - All 3 versions
C Ionescu-Tîrgoviºte - Acta Endocrinologica (Buc), 2009 - 82.76.72.38 Abstract Based on epidemiological, clinic, biochemical and hormonal data (both
personal and international), our personal view is that natural history of
autoimmune type 1 diabetes could include the following stages: 1) The ... Related articles - View as HTML - All 2 versions
S Pradhan, HG Chin, PO Estčve, SE … - Epigenetics, 2009 - mcdb.ucla.edu Post-translational modification (PTM) of histones, such as methylation,
acetylation, phosphorylation, ADP-ribosylation and ubiquitination are shown to
play important regulatory roles in defining the status of eukaryotic gene ... Related articles - View as HTML - All 5 versions
