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Scholar Results 1 - 10 of about 101 related to Arita: Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage. (0.10 sec) 

Rho kinase inhibition by fasudil ameliorates diabetes-induced microvascular damage


R Arita, Y Hata, S Nakao, T Kita, M Miura, S … - Diabetes, 2009 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Localization of RhoA/ROCK and Rho activity were
examined in retinal tissues of rats. Impact of intravitreal fasudil
administration on retinal endothelial nitric oxide synthase (eNOS) and ...
Cited by 7 - Related articles - All 4 versions

Role of TGF-β in proliferative vitreoretinal diseases and ROCK as a therapeutic target

- pnas.org
T Kita, Y Hata, R Arita, S Kawahara, M Miura … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences
Cicatricial contraction of preretinal fibrous membrane is a cause of severe
vision loss in proliferative vitreoretinal diseases such as proliferative
diabetic retinopathy (PDR) and proliferative vitreoretinopathy (PVR). ...
Cited by 5 - Related articles - All 6 versions

Antiangiogenic properties of fasudil, a potent Rho-Kinase inhibitor

- pubget.com [PDF] 
Y Hata, M Miura, S Nakao, S Kawahara, T Kita, … - Japanese journal of ophthalmology, 2008 - Springer
The small GTPase RhoA and its downstream effector, Rho- kinase, play a central
role in diverse cellular functions, including smooth muscle contraction,
cytoskeletal rear- rangement, cell migration, cell proliferation and gene ...
Cited by 2 - Related articles - All 4 versions

Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal …


J Kroll, D Epting, K Kern, CT Dietz, Y Feng, … - American Journal of Physiology- Heart and Circulatory …, 2009 - Am Physiological Soc
Vascular endothelial growth factor (VEGF) is an endothelial-specific growth
factor that activates the small GTPase RhoA. While the role of RhoA for
VEGF-driven endothelial migration and angiogenesis has been studied in ...
Cited by 2 - Related articles - All 3 versions

Chronic hyperglicemia and nitric oxide bioavailability play a pivotal role in pro-atherogenic …

- nih.gov
A Pandolfi, EA De Filippis - Genes & Nutrition, 2007 - Springer
Abstract Diabetes is associated with accelerated athero- sclerosis and
macrovascular complications are a major cause of morbidity and mortality in this
disease. Although our understanding of vascular pathology has lately ...
Cited by 3 - Related articles - BL Direct - All 4 versions

[PDF] Shear stress stimulates phosphorylation of eNOS at Ser1179 by Akt-independent …


YC Boo, G Sorescu, N Boyd, I Shiojima, K … - Journal of Biological Chemistry, 2001 - ASBMB
Page 1. PKA-dependent phosphorylation of eNOS-Ser 1179 by shear stress M1:08789,
Revision - 1 - Shear stress stimulates phosphorylation of eNOS at Ser ...
Cited by 3 - Related articles - All 2 versions

Local cortical tension by myosin II guides 3D endothelial cell branching

- cell.com
RS Fischer, M Gardel, X Ma, RS Adelstein, … - Current Biology, 2009 - Elsevier
A key feature of angiogenesis is directional control of endothelial cell (EC)
morphogenesis and movement [1]. During angiogenic sprouting, endothelial “tip
cells” directionally branch from existing vessels in response to ...
Cited by 3 - Related articles - All 6 versions

Morelloflavone, a biflavonoid, inhibits tumor angiogenesis by targeting rho GTPases and …


X Pang, T Yi, Z Yi, SG Cho, W Qu, D Pinkaew, … - Cancer research, 2009 - AACR
Tumor angiogenesis, the development of new blood vessels from the existing
vasculature, is considered a key step in tumor growth, invasion, and metastasis,
which is required for proper nourishment and removal of metabolic wastes ...
Cited by 4 - Related articles - All 4 versions

Diabetic cardiomyopathy: how much does it depend on AGE?


M Montagnani - British Journal of Pharmacology, 2008 - pubmedcentral.nih.gov
Diabetic cardiomyopathy refers to dysfunction of cardiac muscle in patients with
diabetes that cannot be directly ascribed to hypertension, coronary heart
disease or other defined cardiac abnormalities per se. The development of ...
Cited by 6 - Related articles - BL Direct - All 3 versions

RhoC is essential for angiogenesis induced by hepatocellular carcinoma cells via regulation …


W Wang, F Wu, F Fang, Y Tao, L Yang - Cancer Science, 2008 - ingentaconnect.com
IngentaConnect. ...
Cited by 7 - Related articles - All 4 versions


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