- ►diabetesjournals.org M Kanwar, RA Kowluru - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE—Mitochondrial superoxide levels are elevated in the retina in
diabetes, and manganese superoxide dismutase overexpression prevents the
development of retinopathy. Superoxide inhibits glyceraldehyde-3-phosphate ... Cited by 6 - Related articles - All 3 versions
PS Chan, M Kanwar, RA Kowluru - Journal of diabetes and its complications, 2008 - Elsevier Diabetic retinopathy resists arrest of its progression after reestablishment of
good glycemic control that follows a profound period of poor glycemic control.
The objective of this study was to elucidate the role of inflammation in ... Cited by 2 - Related articles - All 3 versions
- ►iovs.org RJ Walker, JJ Steinle - Investigative Ophthalmology & Visual Science, 2007 - ARVO RESULTS. Isoproterenol treatment significantly decreased protein levels of iNOS,
TNF- , and IL-1B, in rMC-1 cells cultured in high glucose as early as 1 hour,
compared with cells receiving no treatment. PGE2 content was also reduced ... Cited by 3 - Related articles - BL Direct - All 2 versions
B Xu, J Chiu, B Feng, S Chen, S Chakrabarti - Diabetes/Metabolism Reviews - interscience.wiley.com The development of diabetic complications is associated with increased oxidative
stress which may damage DNA leading to the activation of nuclear enzyme poly
(ADP-ribose) polymerase (PARP). PARP overactivation may further exacerbate ... Cited by 6 - Related articles - All 4 versions
ECK Yego, JA Vincent, VP Sarthy, J Busik, S … - Investigative Ophthalmology & Visual Science, 2008 - ARVO Page 1. 1 High Glucose-Induced Glyceraldehyde-3-Phosphate Dehydrogenase Nuclear
Accumulation in Müller Cells is Regulated by Interleukin-1β and Interleukin-6 ... Related articles - All 2 versions
RA Kowluru, PS Chan - Brain Research Bulletin, 2009 - Elsevier Retinal capillary cells undergo apoptosis before pathology characteristic of
retinopathy can be observed, and the appearance of apoptotic capillary cell can
predict the development of pathology. The purpose of this study is to ... Cited by 1 - Related articles - All 2 versions
VR Drel, W Xu, J Zhang, IA Pavlov, H … - Endocrinology, 2009 - Endocrine Soc This study was aimed at evaluating the role for poly(ADP-ribose) polymerase
(PARP) in early ne- phropathy associated with type 1 diabetes. Control and
streptozotocin-diabetic rats were main- tained with or without treatment ... Related articles
RA Kowluru, M Kanwar - Biochemical and Biophysical Research …, 2009 - Elsevier H-Ras, a small molecular weight G-protein, undergoes post-translational
modifications enabling its translocation from cytosol to the membrane.
Hyperglycemia increases apoptosis of retinal capillary cells via activation ... Cited by 1 - Related articles - All 2 versions
ECK Yego, JA Vincent, V Sarthy, JV Busik, S … - Investigative Ophthalmology & Visual Science, 2009 - ARVO RESULTS. High glucose induced IL-1β, weak IL-6, and no TNF production by rMC-1
and HMCs. IL-1β (1–10 ng/mL) significantly increased GAPDH nuclear
accumulation in Müller cells in a concentration-dependent manner within 24 ... Related articles
- ►physiology.org GV Sangle, R Zhao, GX Shen - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Atherosclerotic cardiovascular disease is the number one cause of death for
adults in Western society. Plasminogen activator inhibitor-1 (PAI-1), the major
physiological inhibitor of plasminogen activators, has been implicated in ... Cited by 1 - Related articles - All 3 versions
