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Scholar Results 1 - 10 of about 101 related to Basu: Liver is the site of splanchnic cortisol production in obese nondiabetic humans. (0.10 sec) 

Liver is the site of splanchnic cortisol production in obese nondiabetic humans


R Basu, A Basu, M Grudzien, P Jung, P … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—Ratios of arterial and portal vein D4 cortisol/cortisol total (0.06 ±
0.01 vs. 0.06 ± 0.01) and D4 cortisol/D3 cortisol (1.80 ± 0.14 vs. 1.84 ±
0.14) did not differ, indicating that no visceral cortisol production or ...
Cited by 3 - Related articles - All 3 versions

Cortisol release from adipose tissue by 11β-hydroxysteroid dehydrogenase type 1 in …

- ed.ac.uk [PDF] 
RH Stimson, J Andersson, R Andrew, DN … - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE—11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates
cortisol from cortisone. 11β-HSD1 mRNA and activity are increased in vitro in
subcutaneous adipose tissue from obese patients. Inhibition of 11β-HSD1 is ...
Cited by 5 - Related articles - All 6 versions

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in the inflammatory …


KE Chapman, AE Coutinho, M Gray, JS Gilmour … - Molecular and Cellular Endocrinology, 2009 - Elsevier
Cortisone, a glucocorticoid hormone, was first used to treat rheumatoid
arthritis in humans in the late 1940s, for which Hench, Reichstein and Kendall
were awarded a Nobel Prize in 1950 and which led to the discovery of the ...
Cited by 3 - Related articles - All 3 versions

Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial …


R Basu, DS Edgerton, RJ Singh, A … - Diabetes, 2006 - ncbi.nlm.nih.gov
Eight dogs underwent combined hepatic/portal vein catheterization and infusion
of D4-cortisol in order to determine the relative contributions of the viscera
and liver to splanchnic cortisol production. D4-cortisol concentrations ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Local and systemic glucocorticoid metabolism in inflammatory arthritis


R Hardy, EH Rabbitt, A Filer, P Emery, M … - British Medical Journal, 2008 - ard.bmj.com
Methods: Synovial tissue was taken from patients with RA during joint
replacement surgery. Glucocorticoid metabolism in explants was assessed by
thin-layer chromatography and specific enzyme inhibitors. RT-PCR and ...
Cited by 6 - Related articles - All 4 versions

7-Oxysterols Modulate Glucocorticoid Activity in Adipocytes through Competition for 11 { …


M Wamil, R Andrew, KE Chapman, J Street, … - Endocrinology, 2008 - Endocrine Soc
Obesity is associated with an increased risk of diabetes type 2, dyslipidemia,
and atherosclerosis. These cardiovascular and metabolic abnormalities are
exacerbated by excessive dietary fat, particularly cholesterol and its ...
Cited by 7 - Related articles - All 4 versions

[CITATION] Flier JS2001A transgenic model of visceral obesity and the metabolic syndrome


H Masuzaki, J Paterson, H Shinyama, NM … - Science2942166
Cited by 3 - Related articles

[CITATION] Sö derberg S, Olsson T, Walker BR 2003 Local and systemic impact of transcriptional up- …


DJ Wake, E Rask, DE Livingstone - J Clin Endocrinol Metab
Cited by 2 - Related articles

[CITATION] Sö derberg S, Andrew R, Livingstone DE, Johnson O, Walker BR 2001 Tissue-specific …


E Rask, T Olsson - J Clin Endocrinol Metab
Cited by 2 - Related articles

Skeletal muscle 11 {beta} hydroxysteroid dehydrogenase type 1 activity is upregulated …


C Jang, VR Obeyesekere, FP Alford, WJ Inder - European Journal of Endocrinology, 2009 - eje.org
Objective: Cortisol has been traditionally implicated in the causation of
peri-operative skeletal muscle (SkM) insulin resistance, but cortisol levels
return to normal within 72 h of surgery. Tissue cortisol bioactivity may be ...
Cited by 2 - Related articles - All 6 versions


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