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Scholar Results 1 - 10 of about 101 related to Stimson: Cortisol release from adipose tissue by 11β-hydroxysteroid dehydrogenase type 1 in humans. (0.11 sec) 

Cortisol release from adipose tissue by 11β-hydroxysteroid dehydrogenase type 1 in …

- ed.ac.uk [PDF] 
RH Stimson, J Andersson, R Andrew, DN … - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE—11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) regenerates
cortisol from cortisone. 11β-HSD1 mRNA and activity are increased in vitro in
subcutaneous adipose tissue from obese patients. Inhibition of 11β-HSD1 is ...
Cited by 5 - Related articles - All 6 versions

Liver is the site of splanchnic cortisol production in obese nondiabetic humans


R Basu, A Basu, M Grudzien, P Jung, P … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—Ratios of arterial and portal vein D4 cortisol/cortisol total (0.06 ±
0.01 vs. 0.06 ± 0.01) and D4 cortisol/D3 cortisol (1.80 ± 0.14 vs. 1.84 ±
0.14) did not differ, indicating that no visceral cortisol production or ...
Cited by 3 - Related articles - All 3 versions

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in the inflammatory …


KE Chapman, AE Coutinho, M Gray, JS Gilmour … - Molecular and Cellular Endocrinology, 2009 - Elsevier
Cortisone, a glucocorticoid hormone, was first used to treat rheumatoid
arthritis in humans in the late 1940s, for which Hench, Reichstein and Kendall
were awarded a Nobel Prize in 1950 and which led to the discovery of the ...
Cited by 3 - Related articles - All 3 versions

Splanchnic cortisol production in dogs occurs primarily in the liver: evidence for substantial …


R Basu, DS Edgerton, RJ Singh, A … - Diabetes, 2006 - ncbi.nlm.nih.gov
Eight dogs underwent combined hepatic/portal vein catheterization and infusion
of D4-cortisol in order to determine the relative contributions of the viscera
and liver to splanchnic cortisol production. D4-cortisol concentrations ...
Cited by 5 - Related articles - BL Direct - All 3 versions

Glucocorticoid-mediated effects on metabolism are reversed by targeting 11 beta …


F Salehzadeh, L Al-Khalili, SS Kulkarni, M … - Diabetes/Metabolism Reviews - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ...
Related articles - All 2 versions

8 Glucocorticoids Modulators of Adipose as


NM Morton - Adipose Tissue and Inflammation, 2009 - books.google.com
8 Glucocorticoids Modulators of Adipose as Inflammation Nicholas M. Morton
ContEnts 8.1 Adipose Inflammation in Obesity....................................
............................. 127 8.2 Glucocorticoids and Inflammation...... ...
Related articles

Stress and obesity: the role of the hypothalamic-pituitary-adrenal axis in metabolic disease

- nursing2008.com
M Bose, B Olivan, B Laferrere - Current Opinion in Endocrinology, Diabetes and …, 2009 - journals.lww.com
Introduction and background The prevalence of obesity has increased dramatically
in the USA in the last several decades. Obesity, particularly upper body obesity
(UBO), is associated with type 2 diabetes (T2DM), dyslipidemia, and ...
Related articles - All 5 versions

11 {beta}-Hydroxysteroid Dehydrogenase Type 1 and Its Role in the Hypothalamus-Pituitary …


MS Cooper, PM Stewart - Journal of Clinical Endocrinology & Metabolism, 2009 - Endocrine Soc
Context: 11ß-Hydroxysteroid dehydrogenase (11ß-HSD) enzymes are now
appreciated to be im- portant regulators of hormone action at a tissue level.
11ß-HSD1 is widely expressed and increases glucocorticoid action through ...
Related articles - All 3 versions

Local and systemic glucocorticoid metabolism in inflammatory arthritis


R Hardy, EH Rabbitt, A Filer, P Emery, M … - British Medical Journal, 2008 - ard.bmj.com
Methods: Synovial tissue was taken from patients with RA during joint
replacement surgery. Glucocorticoid metabolism in explants was assessed by
thin-layer chromatography and specific enzyme inhibitors. RT-PCR and ...
Cited by 6 - Related articles - All 4 versions

7-Oxysterols Modulate Glucocorticoid Activity in Adipocytes through Competition for 11 { …


M Wamil, R Andrew, KE Chapman, J Street, … - Endocrinology, 2008 - Endocrine Soc
Obesity is associated with an increased risk of diabetes type 2, dyslipidemia,
and atherosclerosis. These cardiovascular and metabolic abnormalities are
exacerbated by excessive dietary fat, particularly cholesterol and its ...
Cited by 7 - Related articles - All 4 versions


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