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Scholar Results 1 - 10 of about 101 related to Torres: Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalize.... (0.14 sec) 

Restoration of hepatic glucokinase expression corrects hepatic glucose flux and normalizes …


TP Torres, REL Catlin, R Chan, Y Fujimoto, N … - Diabetes, 2009 - Am Diabetes Assoc
RESULTS—ZDF rats compared with ZCL rats have lower hepatic GK activity (11.6
± 1.9 vs. 32.5 ± 3.2 mU/mg protein), marked hyperglycemia (23.9 ± 1.2 vs. 7.4
± 0.3 mmol/l), higher endogenous glucose production (80 ± 3 vs. 38 ± 3 ...
Cited by 1 - Related articles - All 3 versions

A defect in glucose-induced dissociation of glucokinase from the regulatory protein in Zucker …

- physiology.org
JS Shin, TP Torres, REL Catlin, EP Donahue, … - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc
Effect of stimulation of glucokinase (GK) export from the nucleus by small
amounts of sorbitol on hepatic glucose flux in response to elevated plasma
glucose was examined in 6-h fasted Zucker diabetic fatty rats at 10 wk of ...
Cited by 4 - Related articles - BL Direct - All 5 versions

Glucokinase thermolability and hepatic regulatory protein binding are essential factors for …

- jbc.org
MF Pino, KA Kim, KD Shelton, J Lindner, S … - Journal of Biological Chemistry, 2007 - ASBMB
To better understand how glucokinase (GK) missense mutations associated with
human glycemic diseases perturb glucose homeostasis, we generated and
characterized mice with either an activating (A456V) or inactivating ...
Cited by 6 - Related articles - All 7 versions

Contributions of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2 to the …

- physiology.org
VA Payne, C Arden, AJ Lange, L Agius - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc
The insulin-resistant Zucker fa/fa rat has elevated hepatic glycolysis and
activities of glucokinase and phosphofructokinase-2/fructose bisphosphatase-2
(PFK2). The latter catalyzes the formation and degradation of fructose-2,6- ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Activity of hepatic glucose phosphorylating and NADPH generating enzymes in Zucker rats.


R Huupponen, I Karvonen, E Sotaniemi - Diabetes research (Edinburgh, Scotland), 1989 - ncbi.nlm.nih.gov
The activities of hepatic enzymes involved in glucose phosphorylation and NADPH
production were studied in male and female obese Zucker rats (fa/fa) and lean
control animals (Fa/-). The fa/fa animals were heavier and had higher serum ...
Cited by 7 - Related articles

The glucose-6-phosphatase/glucokinase ratio in the liver of obese-diabetic subjects.


F Belfiore, F Romeo, S Iannello, C Salamone - Biochemical medicine and metabolic biology, 1989 - ncbi.nlm.nih.gov
The study of G6Pase and GK activities in human liver (needle biopsies) in
overnight fasted obese NIDDM patients has shown that, while G6Pase was
unchanged, GK was higher (+ 55%, P less than 0.05) than in control ...
Cited by 8 - Related articles - All 2 versions

[PDF] Glucokinase and molecular aspects of liver glycogen metabolism


L Agius - Biochemical Journal, 2008 - eng.auburn.edu
Conversion of glucose into glycogen is a major pathway that contributes to the
removal of glucose from the portal vein by the liver in the postprandial state.
It is regulated in part by the increase in blood-glucose concentration in ...
Cited by 10 - Related articles - View as HTML - All 5 versions

[CITATION] Glucokinase activator RO-4389620 improves plasma glucose concentrations, beta-cell …


RC Bonadonna, C Kapitza, T Heise, A Avogaro, … - Diabetes, 2008
Cited by 3 - Related articles

[CITATION] DESIR Study Group: The common P446L polymorphism in GCKR inversely modulates fasting …


M Vaxillaire, C Cavalcanti-Proença, A … - Diabetes, 2008
Cited by 2 - Related articles

Targeting Hepatic Glucokinase in Type 2 Diabetes


L Agius - Diabetes, 2009 - Am Diabetes Assoc
Glucokinase (hexokinase IV) has a major role in the control of blood glucose
homeostasis because it is the predominant hexokinase expressed in the liver, has
a very high control strength on hepatic glucose disposal (1), and is the ...
Related articles - All 4 versions


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