S Puri, DA Cano, M Hebrok - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE—The Vhlh gene codes for the von Hippel-Lindau protein (VHL), a tumor
suppressor that is a key player in the cellular response to oxygen sensing. In
humans, a germline mutation in the VHL gene leads to the von Hippel-Lindau ... Related articles - All 3 versions
SK PARK, VH HAASE, RS JOHNSON - International journal of oncology, 2007 - cat.inist.fr von Hippel Lindau tumor suppressor regulates hepatic glucose metabolism by controlling
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M NARIMIYA, H YAMADA, I MATSUBA, Y … - Endocrinology, 1982 - Endocrine Soc It has been reported that insulin secretion decreases during hypoxia both in
vivo and in vitro, while an increase in glucagon secretion is found only in
vivo. The effect of acute hypoxia on the secretion of glucagon and insulin ... Cited by 9 - Related articles - All 2 versions
S Fujimoto, K Nabe, M Takehiro, M … - Diabetes Research and Clinical Practice, 2007 - Elsevier Glucose-induced insulin secretion from β-cells is often impaired in diabetic
condition and by exposure to diabetogenic pharmacological agents. In pancreatic
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G Miao, RP Ostrowski, J Mace, J Hough, A … - American Journal of Transplantation, 2006 - interscience.wiley.com More than half of transplanted β-cells undergo apoptotic cell death triggered
by nonimmunological factors within a few days after transplantation. To
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- ►nih.gov JB Regard, H Kataoka, DA Cano, E Camerer, … - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig The in vivo roles of the hundreds of mammalian G protein–coupled receptors
(GPCRs) are incompletely understood. To explore these roles, we generated mice
expressing the S1 subunit of pertussis toxin, a known inhibitor of G i/o ... Cited by 14 - Related articles - BL Direct - All 6 versions
PP Kapitsinou, VH Haase - Cell Death & Differentiation, 2008 - nature.com The von Hippel–Lindau tumor suppressor gene product, pVHL, functions as the
substrate recognition component of an E3-ubiquitin ligase, which targets the
oxygen-sensitive -subunit of hypoxia-inducible factor (HIF) for rapid ... Cited by 16 - Related articles - BL Direct - All 4 versions
DA Cano, S Sekine, M Hebrok - Gastroenterology, 2006 - Elsevier The pancreas is a mixed exocrine and endocrine gland that plays a central role
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C Bonny, R Roduit, S Gremlich, P Nicod, B … - Molecular and cellular endocrinology, 1997 - Elsevier GLUT2 expression is reduced in the pancreatic β-cells of several diabetic
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- ►cshlp.org J Zehetner, C Danzer, S Collins, K Eckhardt, … - Genes & Development, 2008 - genesdev.cshlp.org Insulin secretion from pancreatic β cells is stimulated by glucose metabolism.
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