- ►diabetesjournals.org CC Berthier, H Zhang, ML Schin, A Henger, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—In human glomeruli and tubulointerstitial samples, the Janus kinase
(Jak)-signal transducer and activator of transcription (Stat) pathway was highly
and significantly regulated. Jak-1, -2, and -3 as well as Stat-1 and -3 ... Cited by 2 - Related articles - All 3 versions
KR Bhat, BJ Benton, R Ray - Journal of Applied Toxicology, 2006 - interscience.wiley.com Concurrent activation of poly (ADP-ribose) polymerase (PARP) and DNA ligase was
observed in cultured human epidermal keratinocytes (HEK) exposed to the DNA
alkylating compound sulfur mustard (SM), suggesting that DNA ligase ... Cited by 3 - Related articles - BL Direct - All 7 versions
KC Sourris, JM Forbes - Current Drug Targets, 2009 - ingentaconnect.com Abstract: Diabetes, is a metabolic disorder characterised by chronic
hyperglycaemia, hypertension, dyslipidaemia, micro- albuminuria and
inflammation. Moreover, there are a number of complications associated with ... Cited by 3 - Related articles - All 2 versions
MT Coughlan, DR Thorburn, SA Penfold, A … - Journal of the American Society of Nephrology, 2009 - Am Soc Nephrol Damaged mitochondria generate an excess of superoxide, which may mediate tissue
injury in diabetes. We hypothesized that in diabetic nephropathy, advanced
glycation end-products (AGEs) lead to increases in cytosolic reactive ... Cited by 5 - Related articles - All 4 versions
R Mishra, SN Emancipator, TS Kern, MS … - Biochemical and Biophysical Research …, 2006 - Elsevier Endothelin-1 has been implicated in diabetic kidney injury, but there are few
firm data establishing the temporal and spatial expression of kidney
endothelin-1 in diabetes. We performed an immunohistochemical and ... Cited by 3 - Related articles - All 6 versions
- ►oxfordjournals.org M Meier, J Menne, JK Park, H Haller - Nephrology Dialysis Transplantation, 2007 - ERA-EDTA Diabetic nephropathy is characterized by early vascular dysfunction and
increasing matrix accumulation in the kidney, eventually leading to proteinuria,
glomerulosclerosis and interstitial fibrosis [1]. Over the last decade, our ... Cited by 4 - Related articles - BL Direct - All 2 versions
T Sasase - Drugs Future, 2006 - journals.prous.com Sustained hyperglycemia causes severe diabetic microvascular complications, such
as retinopathy, peripheral neuropathy and nephropathy. Because of the difficulty
in achieving complete euglycemia, a new approach to preventing diabetic ... Cited by 4 - Related articles - All 4 versions
CE Hills, N Al-Rasheed, N Al-Rasheed, GB … - American Journal of Physiology- Renal Physiology, 2008 - Am Physiological Soc Page 1. 1 C-Peptide reverses TGF-β1-Induced changes in Renal Proximal Tubular
Cells: Implications for the treatment of Diabetic Nephropathy ... Cited by 4 - Related articles - All 3 versions
D Wu, F Peng, B Zhang, AJ Ingram, DJ Kelly, … - Journal of the American Society of Nephrology, 2009 - Am Soc Nephrol Accumulation of glomerular matrix is a hallmark of diabetic nephropathy. The
serine/threonine kinase Akt mediates glucose-induced upregulation of collagen I
in mesangial cells through transactivation of the EGF receptor (EGFR). In ... Cited by 6 - Related articles - All 4 versions
R Inagi, M Nangaku, T Miyata - ANNALS-NEW YORK ACADEMY OF SCIENCES, 2005 - interscience.wiley.com Abstract: Diabetic nephropathy is the most common cause of end-stage renal
failure. The primary glomerular changes in diabetic nephropathy are diffuse and
nodular glomerulosclerosis, manifested by an increase in mesangial matrix. ... Cited by 4 - Related articles - BL Direct - All 5 versions
