- ►diabetesjournals.org CR Bruce, AJ Hoy, N Turner, MJ Watt, TL … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE—Skeletal muscle insulin resistance is associated with lipid
accumulation, but whether insulin resistance is due to reduced or enhanced flux
of long-chain fatty acids into the mitochondria is both controversial and ... Cited by 7 - Related articles - All 3 versions
M Schreurs, F Kuipers, FR van der Leij - Obesity reviews: an official journal of the International …, 2009 - interscience.wiley.com Insulin sensitizers like metformin generally act through pathways triggered by
adenosine monophosphate-activated protein kinase. Carnitine palmitoyltransferase
1 (CPT1) controls mitochondrial β-oxidation and is inhibited by ... Related articles - All 2 versions
MC Sugden, MG Zariwala, MJ Holness - Pharmacological Research, 2009 - Elsevier This contribution describes recent advances in our knowledge of the regulatory
interactions between the two major oxidative fuels glucose and lipid. It also
addresses how the metabolic abnormalities associated with insulin ... Related articles - All 2 versions
S Schenk, MP Harber, CR Shrivastava, CF … - The Journal of Physiology, 2009 - Physiological Soc Obesity is characterized by excessive rates of plasma fatty acid mobilization
and uptake, which play a key role in mediating insulin resistance. While weight
loss via diet-only or a diet + exercise program clearly improves insulin ... Related articles - All 5 versions
S Beck Jørgensen, HM O'Neill, K Hewitt, BE … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis Obesity-related insulin resistance is associ- ated with
accumulation of bioactive lipids in skeletal muscle. The AMP-activated protein
kinase (AMPK) regulates lipid oxidation in muscle by inhibiting acetyl-CoA ... Related articles - All 2 versions
[CITATION] Effect of a selective and reversible hepatic CPT1 inhibitor on HOMA index and fasting blood …
MJ Watt, EW Kraegen - Diabetes, 2009 - Am Diabetes Assoc The evidence is now compelling that an excess supply of fatty acids, beyond that
required for energy needs, is a cause of muscle insulin resistance.
Intramyocellular triglyceride accumulation is a marker of excess fatty acid ... Cited by 1 - Related articles - All 3 versions
SB Jorgensen, J Honeyman, JS Oakhill, D … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc The hormone resistin is elevated in obesity and impairs glucose homeostasis.
Here, we examined the effect of oligomerized human resistin on insulin signaling
and glucose metabolism in skeletal muscle and myotubes. This was ... Cited by 1 - Related articles - All 3 versions
- ►uam.es [PDF] P Mera, A Bentebibel, E López-Vinas, AG … - Biochemical Pharmacology, 2009 - Elsevier Central nervous system administration of C75 produces hypophagia and weight loss
in rodents identifying C75 as a potential drug against obesity and type 2
diabetes. However, the mechanism underlying this effect is unknown. Here we ... Cited by 1 - Related articles - All 4 versions
M Schreurs, TH van Dijk, A Gerding, R … - Diabetes, obesity & metabolism, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 1 - Related articles - All 3 versions
