- ►diabetesjournals.org C Leloup, C Tourrel-Cuzin, C Magnan, M Karaca … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Transient glucose increase from 5.5 to 16.7 mmol/l stimulated ROS
generation, which was reversed by antioxidants. Insulin secretion was dose
dependently blunted by antioxidants and highly correlated with ROS levels. ... Cited by 7 - Related articles - All 4 versions
JS Silvestre, BI Lévy - Annales de cardiologie et d'angeiologie, 2006 - Elsevier Les complications cardiovasculaires représentent la première cause de
morbimortalité des patients diabétiques : 80 % des décès de ces malades sont
en rapport direct avec une maladie vasculaire. La capacité à développer ... Cited by 3 - Related articles - All 2 versions
RP Robertson - Trends in Endocrinology & Metabolism, 2009 - Elsevier Clinical management of patients with type 2 diabetes (T2D) successfully prevents
extreme hyperglycemia but does not precisely control glucose levels throughout
the day. The pathogenesis of T2D is akin to a double-barrel shotgun. The ... Related articles - All 2 versions
P Newsholme, D Morgan, E Rebelato, HC … - Diabetologia - Springer Abstract It is now widely accepted that reactive oxygen species (ROS) contribute
to cell and tissue dysfunction and damage in diabetes. The source of ROS in the
insulin secreting pancreatic beta cells has traditionally been considered ... Related articles - All 2 versions
A Carrière, TG Ebrahimian, S Dehez, N Augé, … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 - pt.wkhealth.com From the Université de Toulouse (AC, SD, CJ, MA, SA, MD, CB, EA, YF, VP-B., LP,
LC) UPS, UMR 5241 Métabolisme, Plasticité et Mitochondrie, Toulouse Cedex 4,
France; CNRS (AC, SD, CJ, MA, SA, MD, CB, EA, UF, VP-B., LP, LC) UMR 5241 ... Related articles
A Carriere, TG Ebrahimian, S Dehez, N Auge, C … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2009 - Am Heart Assoc Methods and Results— The use of pharmacological strategies (mitochondrial
inhibitors, antimycin, and rotenone, with or without antioxidants) allowed us to
specifically and precisely modulate mitochondrial ROS generation in ADSCs. ... Related articles - All 5 versions
JH Li, N Zhang, JA Wang - Journal of endocrinological investigation, 2008 - ncbi.nlm.nih.gov BACKGROUND: Bone marrow mesenchymal stem cells (MSC) mediate their protection by
paracrine mechanism under ischemic conditions and anoxic pre-conditioning (AP)
of MSC strongly enhances their survival and regenerative capacity. However, ... Cited by 8 - Related articles - BL Direct - All 3 versions
RL Hull, S Zraika, J Udayasankar, K Aston- … - Diabetologia, 2009 - Springer Abstract Aims/hypothesis Supraphysiological levels of the amyloi- dogenic
peptide human islet amyloid polypeptide have been associated with beta cell
endoplasmic reticulum (ER) stress. However, in human type 2 diabetes, ... Cited by 1 - Related articles - All 2 versions
G Lacraz, F Figeac, J Movassat, N Kassis, J …, 2009 - pubmedcentral.nih.gov Localization of OS markers was performed on whole pancreases. Using islets
isolated from 7-day-old or 2.5-month-old male GK/Par and Wistar control rats, 1)
gene expression was analyzed by qRT-PCR; 2) insulin secretion rate was ... Cited by 1 - Related articles - All 5 versions
D Morgan, E Rebelato, F Abdulkader, MFR … - Endocrinology, 2009 - Endocrine Soc We previously described the presence of nicotinamide adenine dinucleotide
phosphate reduced form [NAD(P)H]oxidase components in pancreatic β-cells and
its activation by glucose, palmitic acid, and proinflammatory cytokines. In ... Cited by 1 - Related articles - All 3 versions