- ►diabetesjournals.org S Torii, N Saito, A Kawano, N Hou, K Ueki, RN … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Adenoviral expression of shPhogrin efficiently decreased its
endogenous expression in pancreatic β-cells. Silencing of phogrin in β-cells
abrogated the glucose-mediated mitogenic effect, which was accompanied by a ... Cited by 1 - Related articles - All 3 versions
P Miettinen, P Ormio, E Hakonen, M Banerjee, … - Biochemical Society Transactions, 2008 - biochemsoctrans.org Pancreatic islet development is impaired in mice lacking EGFRs (epidermal growth
factor receptors). Even partial tissue-specific attenuation of EGFR signalling
in the islets leads to markedly reduced β-cell proliferation and ... Cited by 4 - Related articles - Cached - BL Direct - All 5 versions
S Shimizu, N Saito, A Kubosaki, S SungWook … - Biochemical and Biophysical Research …, 2001 - Elsevier Islet antigen (IA)-2 is a novel autoantigen of insulin-dependent diabetes
mellitus (IDDM), and belongs to a new class within the receptor-type protein
tyrosine phosphatase (PTP) family characterized by lack of PTP enzymatic ... Cited by 4 - Related articles - BL Direct - All 5 versions
C Süß, M Solimena - Exp Clin Endocrinol Diabetes, 2008 - thieme-connect.com Proteomics has rapidly become a major field of research in biology and medicine.
Its main aim is to obtain a global overview of the expression pattern of
proteins and their relationship in any given condition of a biological ... Cited by 4 - Related articles - All 2 versions
S Torii, N Saito, A Kawano, S Zhao, T Izumi, … - Traffic, 2005 - interscience.wiley.com Phogrin is an integral glycoprotein primarily expressed in neuroendocrine cells.
The predominant localization of phogrin is on dense-core secretory granules, and
the lumenal domain has been shown to be involved in its efficient sorting ... Cited by 5 - Related articles - BL Direct - All 3 versions
J Suckale, M Solimena - Front Biosci, 2008 - precedings.nature.com Taken together the Islets of Langerhans form a nutrient sensing network spread
throughout the pancreas. They are tightly connected to the source organ - the
intestine - and the tar- get organs - liver, muscle, and fat cells. The ... Cited by 6 - Related articles - View as HTML - All 5 versions
- ►nih.gov H Mziaut, S Kersting, KP Knoch, WH Fan, M … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Changes in metabolic demands dynamically regulate the total mass of adult
pancreatic β-cells to adjust insulin secretion and preserve glucose
homeostasis. Glucose itself is a major regulator of β-cell proliferation ... Cited by 15 - Related articles - BL Direct - All 7 versions
- ►rupress.org LS Ramos, JH Zippin, M Kamenetsky, J Buck, … - Journal of General Physiology, 2008 - jgp.rupress.org In β cells, both glucose and hormones, such as GLP-1, stimulate production of
the second messenger cAMP, but glucose and GLP-1 elicit distinct cellular
responses. We now show in INS-1E insulinoma cells that glucose and GLP-1 ... Cited by 7 - Related articles - All 6 versions
- ►endojournals.org N Hou, S Torii, N Saito, M Hosaka, T Takeuchi - Endocrinology, 2008 - Endocrine Soc Pancreatic β-cells are susceptible to reactive oxygen species (ROS), which are
known to be generated by high or low glucose (LG), hypoxic, or
cytokine-producing conditions. When we cultured mouse β-cell-derived MIN6 ... Cited by 7 - Related articles - BL Direct - All 4 versions
M Lawrence, C Shao, L Duan, K McGlynn, … - Acta Physiologica, 2008 - interscience.wiley.com Extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) activities are
modulated in a manner that reflects the secretory demand on β cells to
integrate long- and short-term nutrient sensing information. Our studies ... Cited by 9 - Related articles - BL Direct - All 3 versions
