- ►diabetesjournals.org MF Gregor, L Yang, E Fabbrini, BS Mohammed, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Subjects lost 39 ± 9% body wt at 1 year after GBP surgery (P <
0.001), which was associated with a marked improvement in hepatic, skeletal
muscle, and adipose tissue insulin sensitivity. Markers of ER stress in ... Cited by 9 - Related articles - All 4 versions
- ►diabetesjournals.org G Boden, X Duan, C Homko, EJ Molina, WW … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Proteomic analysis revealed 19 differentially upregulated proteins in
fat of obese subjects. Three of these proteins were the ER stress–related
unfolded protein response (UPR) proteins calreticulin, protein disulfide- ... Cited by 23 - Related articles - All 5 versions
- ►endojournals.org NK Sharma, SK Das, AK Mondal, OG Hackney, … - Journal of Clinical Endocrinology & Metabolism, 2008 - Endocrine Soc Results: Adipocyte expression of most markers of ER stress, including chaperones
downstream of activating transcription factor 6, were significantly correlated
with BMI and percent fat (r > 0.5; P < 0.00001). Phosphorylation of ... Cited by 11 - Related articles - All 4 versions
- ►pnas.org E Bobrovnikova-Marjon, G Hatzivassiliou, C … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences The role of the endoplasmic reticulum stress-regulated kinase, PERK, in mammary
gland function was assessed through generation of a targeted deletion in mammary
epithelium. Characterization revealed that PERK is required for functional ... Cited by 4 - Related articles - All 5 versions
T Hosoi, M Sasaki, T Miyahara, C Hashimoto, … - Molecular pharmacology, 2008 - ASPET Leptin is an important circulating signal for inhibiting food intake and body
weight gain. In recent years, "leptin resistance" has been considered to be one
of the main causes of obesity. However, the detailed mechanisms of leptin ... Cited by 6 - Related articles - All 3 versions
S Oyadomari, HP Harding, Y Zhang, M … - Cell Metab, 2008 - cell.com The molecular mechanisms linking the stress of unfolded proteins in the
endoplasmic reticulum (ER stress) to glucose intolerance in obese animals are
poorly understood. In this study, enforced expression of a translation ... Cited by 16 - Related articles - Cached - All 7 versions
K Yoshiuchi, H Kaneto, T Matsuoka, K Kohno, … - Biochemical and Biophysical Research …, 2008 - Elsevier Type 2 diabetes is one of the most prevalent and serious metabolic diseases in
the world, and insulin resistance and pancreatic β-cell dysfunction are the
hallmarks of the disease. It has been suggested that endoplasmic reticulum ... Cited by 9 - Related articles - All 5 versions
- ►pbworks.com [PDF] SM Colgan, D Tang, GH Werstuck, RC Austin - International Journal of Biochemistry and Cell Biology, 2007 - Elsevier Sterol regulatory element binding protein-2 (SREBP-2) is a membrane-bound
transcription factor that upon proteolytic processing can activate the
expression of genes involved in cholesterol biosynthesis and uptake. We as ... Cited by 18 - Related articles - All 3 versions
- ►diabetesjournals.org G Boden - Diabetes, 2009 - Am Diabetes Assoc Obesity, which has reached epidemic proportions in the US and is increasing
worldwide, is closely associated with insulin resistance (peripheral and
hepatic) and with a state of low-grade inflammation, the latter ... Related articles - All 3 versions
