- ►diabetesjournals.org M Mitsuishi, K Miyashita, A Muraki, H Itoh - Diabetes, 2009 - Am Diabetes Assoc RESULTS—C2C12 cells treated with 10 −8 –10 −6 mol/l AngII reduced the
mitochondrial content associated with downregulation of the genes involved in
mitochondrial biogenesis. The action of AngII was diminished by blockade of ... Cited by 1 - Related articles - All 3 versions
C Trapp, AK McCullough, B Epe - … Research-Fundamental and Molecular Mechanisms of …, 2007 - Elsevier Mitochondrial DNA (mtDNA) is assumed to be highly prone to damage by reactive
oxygen species (ROS) because of its location in close proximity to the
mitochondrial electron transport chain. Accordingly, mitochondrial ... Cited by 4 - Related articles - All 2 versions
NA Guliaeva, EA Kuznetsova, AI Gaziev - Biofizika - ncbi.nlm.nih.gov It has been suggested in a number of investigations that the high vulnerability
of mitochondrial DNA to reactive oxygen species and other damaging agents is due
to the absence in mitochondria of histones complexed with DNA. In the ... Cited by 4 - Related articles
- ►ncku.edu.tw [PDF] NC de Souza-Pinto, PA Mason, K Hashiguchi, … - DNA repair, 2009 - Elsevier Maintenance of the mitochondrial genome (mtDNA) is essential for proper cellular
function. The accumulation of damage and mutations in the mtDNA leads to
diseases, cancer, and aging. Mammalian mitochondria have proficient base ... Cited by 4 - Related articles - All 3 versions
AE Civitarese, SR Smith, E Ravussin - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Recent findings: Insulin resistance is central to many chronic metabolic
diseases, including obesity, type 2 diabetes, dyslipidemia, and hypertension.
Insulin resistance in skeletal muscle is associated with lower ... Cited by 4 - Related articles - BL Direct - All 2 versions
AD Van Eyk, D Litthauer, W Oelofsen - The International journal of biochemistry, 1992 - ncbi.nlm.nih.gov 1. A procedure is described for the purification of catalase and a peroxidase
active fraction from human white adipose tissue. 2. Gel electrophoresis on
SDS-PAGE revealed relative molecular masses of 202,900 and 208,600 for the ... Cited by 4 - Related articles - All 2 versions
YC Jang, HV Remmen - Experimental Gerontology, 2009 - Elsevier A substantial body of evidence has accumulated over the past 35 years in support
of a role for oxidative damage to the mitochondrial respiratory chain and
mitochondrial DNA in the determination of mammalian lifespan. The goal of ... Cited by 4 - Related articles - All 2 versions
- ►nih.gov I Shokolenko, N Venediktova, A Bochkareva, … - Nucleic Acids Research, 2009 - Oxford Univ Press Mitochondrial DNA (mtDNA) is located in close proximity of the respiratory
chains, which are the main cellular source of reactive oxygen species (ROS). ROS
can induce oxidative base lesions in mtDNA and are believed to be an ... Cited by 4 - Related articles - All 7 versions
- ►nih.gov A Kukat, C Kukat, J Brocher, I Schafer, G … - Nucleic Acids Research, 2008 - Oxford Univ Press Eukaryotic cells devoid of mitochondrial DNA ( 0 cells) were originally
generated under artificial growth conditions utilizing ethidium bromide. The
chemical is known to intercalate preferentially with the mitochondrial ... Cited by 4 - Related articles - BL Direct - All 6 versions
MF Alexeyev, N Venediktova, V Pastukh, G … - Mitochondrion, 2006 - Elsevier The T8993G transversion in mitochondrial DNA, which affects subunit 6 of
mitochondrial ATPase, is believed to be the most commonly identified mtDNA
mutation in children. Two diseases, NARP (Neuropathy, Ataxia and Retinitis ... Cited by 5 - Related articles - BL Direct - All 4 versions
