- ►diabetesjournals.org AV Matveyenko, T Gurlo, M Daval, AE Butler, … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE Obesity is a known risk factor for type 2 diabetes. However, most
obese individuals do not develop diabetes because they adapt to insulin
resistance by increasing β-cell mass and insulin secretion. Islet ... Cited by 3 - Related articles - All 3 versions
- ►diabetesjournals.org T Alquier, V Poitout - Diabetes, 2009 - Am Diabetes Assoc Since its deorphanization in 2003 (1,2), the fatty acid receptor GPR40
(FFAR1/FFA1) has drawn considerable attention as a potential therapeutic target
for type 2 diabetes. Because fatty acids acutely amplify insulin secretion ... Cited by 2 - Related articles - All 3 versions
- ►endojournals.org K Fujiwara, F Maekawa, K Dezaki, M Nakata, … - Endocrinology, 2007 - Endocrine Soc The effect of long-chain free fatty acids on glucagon secretion from islet
-cells has been a controversial issue. This study examined direct effects of
oleic acid (OA) on glucagon release from rat pancreatic islets and on ... Cited by 2 - Related articles - BL Direct - All 3 versions
M Johansson, J Olerud, L Jansson, PO … - Endocrinology, 2009 - Endocrine Soc Transplantation of pancreatic islets is clinically used to treat type 1 diabetes
but requires multiple donors. Previous experimental studies demonstrated that
transplanted islets have a low blood vessel density, which leads to a ... Cited by 2 - Related articles - All 5 versions
CFH Van Schravendijk, R Kiekens, L Heylen, … - Biochemical and biophysical research communications, 1994 - grande.nal.usda.gov Record Detail. Return to previous page, Save: Title: Amino-acid responsiveness in
beta cell subpopulations with different sensitivity to glucose. ... Cited by 2 - Related articles - Cached - BL Direct - All 4 versions
V Poitout - Biochemical Society Transactions, 2008 - biochemsoctrans.org The glucolipotoxicity hypothesis postulates that chronically elevated levels of
glucose and fatty acids adversely affect pancreatic β-cell function and thereby
contribute to the deterioration of insulin secretion in Type 2 diabetes. ... Cited by 2 - Related articles - Cached - All 5 versions
J Lau, C Kampf, G Mattsson, D Nyqvist, M … - Cell Transplantation, 2009 - ingentaconnect.com Pancreatic islets implanted heterotopically (ie, into the kidney, spleen, or
liver) become poorly revascularized following transplantation. We hypothesized
that islets implanted into the pancreas would become better revascularized. ... Cited by 2 - Related articles - All 2 versions
V Fürstova, T Kopska, RFL James, J Kovar - Life sciences, 2008 - Elsevier We tested the effects of various types of fatty acids, differing in the degree
of saturation and in the cis/trans configuration of the double bond, on the
growth and viability of NES2Y cells (a human pancreatic β-cell line). We ... Cited by 2 - Related articles - All 3 versions
B Lozanoska-Ochser, NJ Klein, GC Huang, … - The Journal of Immunology, 2008 - Am Assoc Immnol Pancreatic islet endothelial cells (ECs) form the barrier across which
autoreactive T cells transmigrate during the development of islet inflammation
in type 1 diabetes. Little is known about the immune phenotype of islet ECs ... Cited by 2 - Related articles - All 2 versions
- ►diabetesjournals.org H Zhou, T Zhang, M Bogdani, E Oseid, S … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Glucagon (area under the curve) responses to hypoglycemia in the H
group (8,839 ± 1,988 pg/ml per 90 min) were significantly less than in normal
rats (40,777 ± 8,192; P < 0.01). Fasting significantly decreased hepatic ... Cited by 2 - Related articles - All 4 versions
