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Scholar Results 1 - 10 of about 40 related to Zheng: Protective Effect of Perindopril on Diabetic Retinopathy Is Associated With Decreased.... (0.15 sec) 

Protective Effect of Perindopril on Diabetic Retinopathy Is Associated With …

- diabetesjournals.org
Z Zheng, H Chen, G Ke, Y Fan, H Zou, X Sun, Q Gu, X … - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE This study aimed to verify whether the decreased vascular endothelial growth factor
(VEGF)–to–pigment epithelium–derived factor (PEDF) ratio can serve as an indicator for the
protective effect of angiotensin-converting enzyme inhibitors (ACEIs) on diabetic ...
Cited by 1 - Related articles - All 2 versions

Vascular NAD (P) H Oxidase Activation in Diabetes: A Double-Edged Sword in …

- cardiovascres.org
L Gao, GE Mann - Cardiovascular Research, 2009 - cardiovascres.oxfordjournals.org
Oxidative stress mediated by hyperglycaemia-induced generation of reactive oxygen species
(ROS) contributes significantly to the development and progression of diabetes and related vascular
complications. NAD(P)H oxidase has been implicated as the major source of ROS ...
Cited by 8 - Related articles - All 6 versions

Pigment-epithelium-derived factor (PEDF) inhibits angiotensin-II-induced vascular …


S Yamagishi, T Matsui, K Nakamura, T Yoshida, K … - Microvascular research, 2006 - Elsevier
Angiotensin II (Ang II), the dominant effector of the renin–angiotensin system, elicits numerous
inflammatory-proliferative responses, thereby being involved in angiogenesis. T cells play an
important role in angiogenesis as well by delivering vascular endothelial growth factor ( ...
Cited by 8 - Related articles - All 3 versions

Upregulation of PEDF expression by PARP inhibition contributes to the decrease in …


H Chen, W Jia, X Xu, Y Fan, D Zhu, H Wu, Z Xie, Z … - … and Biophysical Research …, 2008 - Elsevier
Poly(ADP-ribose)polymerase (PARP) inhibitors decrease angiogenesis through reducing vascular
endothelium growth factor (VEGF) induced proliferation, migration, and tube formation of human
umbilical vein endothelial cells (HUVECs). In contrast to VEGF, pigment ...
Cited by 3 - Related articles - All 4 versions

Role of soluble vascular endothelial growth factor receptor-1 in the vitreous in …


N Matsunaga, Y Chikaraishi, H Izuta, N Ogata, M … - Ophthalmology, 2008 - Elsevier
PURPOSE: To determine the vitreous level of soluble vascular endothelial growth factor
receptor-1 (sVEGFR-1) in patients with proliferative diabetic retinopathy (PDR) or idiopathic macular
hole (MH). Furthermore, to investigate the relationships among sVEGFR-1, vascular ...
Cited by 2 - Related articles - All 29 versions

PEDF inhibits JAK2/STAT3-mediated VEGF upregulation under high glucose …


Z Zheng, H Chen, H Zhao… - Investigative Ophthalmology & Visual Science, 2009 - ARVO
Page 1. 0 PEDF inhibits JAK2/STAT3-mediated VEGF upregulation under high glucose
condition through a mitochondrial ROS pathway in vitro Zhi Zheng 1* , Haibing Chen 2* ,
Hui Zhao 1 , Kun Liu 1 , Dawei Luo 1 , Yongdong Chen 1 , Yihui Chen 1 , ...
Related articles - All 2 versions

Renal microvascular injury in diabetes: RAGE and redox signaling


MT Coughlan, ME Cooper, JM Forbes - Antioxidants & Redox …, 2007 - liebertonline.com
D IABETES MELLITUS is currently at epidemic proportions in Western countries and is an emerging
health problem in developing nations. Furthermore, the number of people with diabetes is predicted
to double within the next 10 years (85, 140). It is the end organ injury as a result of ...
Cited by 10 - Related articles - BL Direct - All 3 versions

The role of PPARs in the microvascular dysfunction in diabetes


A Vinik, H Parson, J Ullal - Vascular pharmacology, 2006 - Elsevier
There is a major defect in skin blood flow (SkBF) in people with type 2 diabetes (T2DM). This
defect is associated with relatively normal nitric oxide (NO) production in the skin. The abnormal
blood flow cosegregates with hypertension, dyslipidemia, abnormal fatty acid ...
Cited by 10 - Related articles - All 3 versions

Expression modification of uncoupling proteins and MnSOD in retinal endothelial …


Y Cui, X Xu, H Bi, Q Zhu, J Wu, X Xia, Q Ren, PCP … - Experimental eye …, 2006 - Elsevier
Uncoupling proteins (UCPs) are mitochondrial transporters present in the inner membrane of
mitochondria. They belong to the family of anion mitochondrial carriers. UCPs could act as proton
carriers activated by metabolites and create a shunt between complexes of the respiratory ...
Cited by 18 - Related articles - All 3 versions

PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human …

- cardiovascres.org
TC Ho, SL Chen, YC Yang, CL Liao, HC … - Cardiovascular …, 2007 - cardiovascres.org
Methods and results HUVECs pretreated with either PPAR antagonist or PPAR small interfering
RNA (siRNA) suppressed PEDF-induced apoptosis as determined by TUNEL assay, annexin
V-FITC/PI staining, and cleavage of procaspase-8, -9, -3. PEDF sequentially induced ...
Cited by 21 - Related articles - All 6 versions


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