- ►diabetesjournals.org JH Hwang, DW Kim, EJ Jo, YK Kim, YS Jo, JH … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE Nicotinamide adenine dinucleotides (NAD + and NADH) play a crucial
role in cellular energy metabolism, and a dysregulated NAD + -to-NADH ratio is
implicated in metabolic syndrome. However, it is still unknown whether a ... Cited by 1 - Related articles - All 3 versions
- ►endojournals.org Y Kamei, S Miura, T Suganami, F Akaike, S … - Endocrinology, 2008 - Endocrine Soc Sterol regulatory element binding protein 1c (SREBP1c) is a master regulator of
lipogenic gene expression in liver and adipose tissue, where its expression is
regulated by a heterodimer of nuclear receptor-type transcription factors ... Cited by 9 - Related articles - BL Direct - All 2 versions
DS Edgerton, KM Johnson, AD Cherrington - Frontiers in bioscience: a journal and virtual library, 2009 - ncbi.nlm.nih.gov Diabetes is a complex disease involving multiple organs with dysregulation in
glucose and lipid metabolism. Hepatic insulin insensitivity can contribute to
elevated fasting glucose levels and impaired glucose tolerance in ... Cited by 3 - Related articles
Z Cheng, S Guo, K Copps, X Dong, R … - Nature Medicine, 2009 - nature.com Type 2 diabetes is a complex disease that is marked by the dysfunction of
glucose and lipid metabolism. Hepatic insulin resistance is especially
pathogenic in type 2 diabetes, as it dysregulates fasting and postprandial ... Related articles - All 3 versions
- ►cell.com XC Dong, KD Copps, S Guo, Y Li, R Kollipara … - Cell metabolism, 2008 - Elsevier The forkhead transcription factor Foxo1 regulates expression of genes involved
in stress resistance and metabolism. To assess the contribution of Foxo1 to
metabolic dysregulation during hepatic insulin resistance, we disrupted ... Cited by 12 - Related articles - All 11 versions
- ►jbc.org [PDF] L Lumeng, J Bremer, EJ Davis - Journal of Biological Chemistry, 1976 - ASBMB Page 1. THE ,JOUHNAL OF BIOLOGICAL CHEMISTRY Vol. 251, So. 2, Issue of hnuary 25.
pp. 277-284, 1976 Printed in USA Suppression of the Mitochondrial Oxidation of ... Cited by 17 - Related articles - All 3 versions
A Kamagate, S Qu, G Perdomo, D Su, DH Kim … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Excessive production of triglyceride-rich VLDL is attributable to
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WS Kunz - Biochimica et biophysica acta, 1988 - ncbi.nlm.nih.gov A new method permitting the simultaneous evaluation of the redox states of
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liver mitochondria by two-channel fluorimetry is described. It is shown ... Cited by 17 - Related articles - All 2 versions
- ►utsouthwestern.edu [PDF] MS Brown, JL Goldstein - Cell metabolism, 2008 - Elsevier Humans with type 2 diabetes mellitus exhibit the classic triad of
hyperinsulinemia, hyperglycemia, and hypertriglyceridemia. Hyperglycemia in the
face of hyperinsulinemia is attributed to insulin resistance. In diabetic ... Cited by 20 - Related articles - All 16 versions
- ►cell.com N Kubota, T Kubota, S Itoh, H Kumagai, H … - Cell Metabolism, 2008 - Elsevier Insulin receptor substrate (Irs) mediates metabolic actions of insulin. Here, we
show that hepatic Irs1 and Irs2 function in a distinct manner in the regulation
of glucose homeostasis. The PI3K activity associated with Irs2 began to ... Cited by 20 - Related articles - All 8 versions
