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Scholar Results 1 - 10 of about 101 related to Xie: MicroRNAs induced during adipogenesis that accelerate fat cell development are downregulated.... (0.13 sec) 

MicroRNAs induced during adipogenesis that accelerate fat cell development are …


H Xie, B Lim, HF Lodish - Diabetes, 2009 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS Using miRNA microarrays, we profiled the expression
of >370 miRNAs during adipogenesis of preadipocyte 3T3-L1 cells and adipocytes
from leptin deficient ob/ob and diet-induced obese mice. Changes in key ...
Cited by 7 - Related articles - All 3 versions

MicroRNA expression in human omental and subcutaneous adipose tissue


N Klöting, S Berthold, P Kovacs, MR Schön, … - PLoS ONE, 2009 - pubmedcentral.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs, that play important regulatory
roles in a variety of biological processes, including development,
differentiation, apoptosis, and metabolism. In mammals, miRNAs have been ...
Cited by 3 - Related articles - All 5 versions

Identification of glucose-regulated miRNAs from pancreatic β cells reveals a role for miR-30d …

- cshlp.org
X Tang, L Muniappan, G Tang, S Özcan - Rna, 2009 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are small noncoding ribonucleotides that bind mRNAs and
function mainly as translational repressors in mammals. MicroRNAs have been
implicated to play a role in many diseases, including diabetes. Several ...
Cited by 8 - Related articles - All 4 versions

MicroRNA let-7 Regulates 3T3-L1 Adipogenesis


T Sun, M Fu, AL Bookout, SA Kliewer, DJ … - Molecular Endocrinology, 2009 - Endocrine Soc
Differentiation of 3T3-L1 cells into adipocytes involves a highly orchestrated
series of events including clonal expansion, growth arrest, and terminal
differentiation. The mechanisms coordinating these different steps are not ...
Cited by 7 - Related articles - All 3 versions

miR-375 targets 3′-phosphoinositide–dependent protein kinase-1 and regulates glucose- …

- nih.gov
A El Ouaamari, N Baroukh, GA Martens, P … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—MicroRNAs are short, noncoding RNAs that regulate gene expression.
We hypothesized that the phosphatidylinositol 3-kinase (PI 3-kinase) cascade
known to be important in β-cell physiology could be regulated by ...
Cited by 10 - Related articles - All 5 versions

Alterations in MicroRNA Expression Contribute to Fatty Acid–Induced Pancreatic β-Cell …

- nih.gov
P Lovis, E Roggli, DR Laybutt, S Gattesco, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Prolonged exposure of the β-cell line MIN6B1 and pancreatic islets to
palmitate causes a time- and dose-dependent increase of miR34a and miR146.
Elevated levels of these miRNAs are also observed in islets of diabetic ...
Cited by 8 - Related articles - All 4 versions

miR-375 maintains normal pancreatic α-and β-cell mass

- pnas.org
MN Poy, J Hausser, M Trajkovski, M Braun, S … - Proceedings of the National Academy of Sciences, 2009 - National Acad Sciences
Altered growth and development of the endocrine pancreas is a frequent cause of
the hyperglycemia associated with diabetes. Here we show that microRNA-375
(miR-375), which is highly expressed in pancreatic islets, is required for ...
Cited by 9 - Related articles - All 12 versions

A role of miR-27 in the regulation of adipogenesis


Q Lin, Z Gao, RM Alarcon, J Ye, Z Yun - FEBS J, 2009 - interscience.wiley.com
MicroRNAs (miRNAs) are involved in a plethora of important biological processes,
from embryonic development to homeostasis in adult tissues. Recently, miRNAs
have emerged as a class of epigenetic regulators of metabolism and energy ...
Cited by 5 - Related articles - All 3 versions

Role of microRNAs in obesity and the metabolic syndrome


HM Heneghan, N Miller, MJ Kerin - Obesity reviews: an official journal of the International …, 2009 - interscience.wiley.com
Obesity and the metabolic syndrome are major public health concerns, and present
a formidable therapeutic challenge. Many patients remain recalcitrant to
conventional lifestyle changes and medical therapies. Bariatric surgery has ...
Related articles - All 2 versions

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice


E Zhao, MP Keller, ME Rabaglia, AT Oler, DS … - Mammalian Genome, 2009 - Springer
Abstract Type 2 diabetes results from severe insulin resistance coupled with a
failure of b cells to compensate by secreting sufficient insulin. Multiple
genetic loci are involved in the development of diabetes, although the ...
Cited by 1 - Related articles - All 2 versions


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