- ►diabetesjournals.org LM Lauffer, R Iakoubov, PL Brubaker - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE Intestinal L-cells secrete the incretin glucagon-like peptide-1
(GLP-1) in response to ingestion of nutrients, especially long-chain fatty
acids. The Gαs-coupled receptor GPR119 binds the long-chain fatty acid ... Cited by 6 - Related articles - All 4 versions
H Lan, G Vassileva, A Corona, L Liu, H Baker … - Journal of Endocrinology, 2009 - Soc Endocrinology G protein-coupled receptor 119 (GPR119) is expressed in pancreatic islets and
intestine, and is involved in insulin and incretin hormone release.
GPR119-knockout (Gpr119 –/– ) mice were reported to have normal islet ... Cited by 5 - Related articles - All 3 versions
Y Ning, K O'Neill, H Lan, L Pang, LX Shan, … - British Journal of Pharmacology, 2008 - pubmedcentral.nih.gov GPR119 is a G protein-coupled receptor that is preferentially expressed in islet
cells and mediates insulin secretion. Oleoyl-lysophosphatidylcholine and
oleoylethanolamide (OEA) act as endogenous ligands for this receptor, ... Cited by 6 - Related articles - All 6 versions
G Semple, B Fioravanti, G Pereira, I Calderon … - Journal of Medicinal Chemistry, 2008 - pubs.acs.org GPR119 is a rhodopsin-like GPCR expressed in pancreatic β-cells and incretin
releasing cells in the GI tract. As with incretins, GPR119 increases cAMP levels
in these cell types, thus making it a highly attractive potential target ... Cited by 6 - Related articles - All 3 versions
B Galan-Rodriguez, J Suarez, R Gonzalez- … - Neuropharmacology, 2009 - Elsevier Oleoylethanolamide (OEA), agonist of nuclear PPAR-α receptors and antagonist of
vanilloid TRPV1 receptors, has been reported to show cytoprotective properties.
In this study, OEA-induced neuroprotection has been tested in vitro and in ... Cited by 2 - Related articles - All 2 versions
YIH Sakamoto, SMK Kawakami, TMK Miyamoto … - Biochemical and Biophysical Research …, 2006 - genome.tokushima-u.ac.jp The GPR119 was recently shown to be activated by oleoylethanolamide (OEA), a
naturally occurring bioactive lipid with hypophagic and anti-obesity effects. In
this study, we have cloned and characterized its murine counterpart, ... Cited by 17 - Related articles - View as HTML - All 4 versions
LS Doshi, MK Brahma, SG Sayyed, AV Dixit, … - Metabolism: clinical and experimental, 2009 - ncbi.nlm.nih.gov Recently, several in vitro studies have shown that GPR40 receptor activation by
free fatty acids (FFAs) results in glucose-dependent insulin secretion. However,
whether GPR40 receptor activation results in glucose-dependent insulin ... Cited by 3 - Related articles - All 6 versions
HA Overton, MCT Fyfe, C Reynet - British journal of pharmacology, 2008 - pubmedcentral.nih.gov GPR119 is a G protein-coupled receptor expressed predominantly in the pancreas
(β-cells) and gastrointestinal tract (enteroendocrine cells) in humans.
De-orphanization of GPR119 has revealed two classes of possible endogenous ... Cited by 15 - Related articles - BL Direct - All 6 versions
F Borrelli, AA Izzo - Best Practice & Research Clinical Endocrinology & …, 2009 - Elsevier Acylethanolamides (AEs) are a group of lipids occurring in both plants and
animals. The best-studied AEs are the endocannabinoid anandamide (AEA), the
anti-inflammatory compound palmitoylethanolamide (PEA), and the potent ... Cited by 5 - Related articles - All 23 versions
R Brownlie, R Mayers, J Pierce, A Marley, D … - Biochemical Society Transactions, 2008 - biochemsoctrans.org GPR40 (G-protein-coupled receptor 40) has been shown to be a physiologically
relevant receptor for long-chain fatty acids. It is a family A G-protein-coupled
receptor highly expressed in the β-cell where it increases insulin ... Cited by 5 - Related articles - Cached - All 4 versions
