- ►diabetesjournals.org S Costes, B Vandewalle, C Tourrel-Cuzin, C … - Diabetes, 2009 - Am Diabetes Assoc OBJECTIVE In type 2 diabetes, chronic hyperglycemia is detrimental to β-cells,
causing apoptosis and impaired insulin secretion. The transcription factor
cAMP-responsive element–binding protein (CREB) is crucial for β-cell ... Cited by 1 - Related articles - All 2 versions
- ►jbc.org N Ozgen, M Obreztchikova, J Guo, H … - Journal of Biological Chemistry, 2008 - ASBMB Many growth regulatory stimuli promote cAMP response element-binding protein
(CREB) Ser 133 phosphorylation, but the physiologically relevant CREB-Ser 133
kinase(s) in the heart remains uncertain. This study identifies a novel ... Cited by 4 - Related articles - All 4 versions
VO Rybin, J Guo, SF Steinberg - Journal of Biological Chemistry, 2009 - ASBMB Protein kinase D1 (PKD1) is a physiologically important signaling enzyme that is
activated via protein kinase C-dependent trans-phosphorylation of the activation
loop at Ser 744 and Ser 748 followed by PKD1 autophosphorylation at Ser 916 ... Cited by 6 - Related articles - All 3 versions
R Jacamo, J Sinnett-Smith, O Rey, RT … - J Biol Chem, 2008 - ASBMB From Division of Digestive Diseases, Department of Medicine, David Geffen School
of Medicine, CURE: Digestive Diseases Research Center and Molecular Biology
Institute, University of California, Los Angeles, CA 90095 Running title: ... Cited by 9 - Related articles - All 2 versions
- ►critcaremed.org J Guo, Z Gertsberg, N Ozgen, SF Steinberg - Circulation Research, 2009 - Am Heart Assoc This relatively broad classification of hypertrophy as physiological or
pathological has been useful from an experimental standpoint. However, it fails
to adequately describe most clinically reactive hypertrophies in humans ... Cited by 3 - Related articles - All 5 versions
N Ozgen, AN Plotnikov, IN Shlapakova, P … - Circulation, 2007 - Am Heart Assoc Methods and Results: Neonatal rat cardiac myocytes (NRCM) were stimulated with H
2 O 2 . A gradual decrease of CREB protein began 30m after onset of H 2 O 2 :
maximum decrease was at 2h (Fig). There were also increases of ... Cited by 1 - Related articles
N Ozgen, J Guo, Z Gertsberg, P Danilo Jr, MR … - Molecular Pharmacology, 2009 - ASPET Reactive oxygen species (ROS) exert pleiotropic effects on a wide array of
signaling proteins that regulate cellular growth and apoptosis. This study shows
that long-term treatment with a low concentration of H 2 O 2 leads to the ... Related articles - All 3 versions
DM Valks, TJ Kemp, A Clerk - Journal of Biological Chemistry, 2003 - ASBMB Oxidative stress promotes cardiac myocyte apoptosis through the mitochondrial
death pathway. Since Bcl-2 family proteins are key regulators of apoptosis, we
examined the effects of H 2 O 2 on the expression of principal Bcl-2 family ... Cited by 12 - Related articles - All 3 versions
- ►cardiovascres.org KW Patberg, MN Obreztchikova, SF Giardina, … - Cardiovascular research, 2005 - cardiovascres.org Objective: Long-term cardiac memory (LTCM), expressed as a specific pattern of
T-wave change on ECG, is associated with 1) reduced transient outward potassium
current (I to ), 2) reduced mRNA for the pore-forming protein of I to , ... Cited by 15 - Related articles - All 7 versions
BL Wagner, A Bauer, G Schütz, M Montminy - Journal of Biological Chemistry, 2000 - ASBMB A number of second messenger pathways propagate inductive signals via
protein-protein interactions that are phosphorylation-dependent. The second
messenger, cAMP, for example, promotes cellular gene expression via the ... Cited by 14 - Related articles - All 4 versions
