- ►diabetesjournals.org E Zherebitskaya, E Akude, DR Smith, P … - Diabetes, 2009 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS Lumbar dorsal root ganglia sensory neurons from
normal or 3- to 5-month streptozotocin (STZ)-diabetic rats were cultured with 10
or 25–50 mmol/l glucose. Cell survival and axon outgrowth were assessed. ... Cited by 5 - Related articles - All 3 versions
RVS Rajala, A Rajala, RS Brush, NP Rotstein, … - Journal of neurochemistry, 2009 - pubmedcentral.nih.gov The insulin receptor (IR) and IR signaling proteins are widely distributed
throughout the central nervous system. IR signaling provides a trophic signal
for transformed retinal neurons in culture and we recently reported that ... Cited by 1 - Related articles - All 4 versions
T Tosaki, H Kamiya, Y Yasuda, K Naruse, K … - Experimental Neurology, 2008 - Elsevier Immortalized mouse Schwann cells (IMS) were cultured under 5.5 mM glucose (NG)
or 30 mM glucose (HG) conditions for 4 days. IMS-conditioned media (IMS-media)
were added to the culture media of neurons isolated from 8-week-old DDY ... Cited by 2 - Related articles - All 2 versions
G Li, A Rajala, AF Wiechmann, RE Anderson, … - Journal of Neurochemistry, 2008 - ingentaconnect.com Akt is a phospholipid-binding protein and the downstream effector of the
phosphoinositide 3-kinase (PI3K) pathway. Akt has three isoforms: Akt1, Akt2,
and Akt3. All of these isoforms are expressed in rod photoreceptor cells, ... Cited by 2 - Related articles - All 2 versions
C Punzo, K Kornacker, CL Cepko - Nat Neurosci, 2009 - genepath.med.harvard.edu Retinitis pigmentosa is an incurable retinal disease that leads to blindness.
One puzzling aspect concerns the progression of the disease. Although most
mutations that cause retinitis pigmentosa are in rod ... Cited by 5 - Related articles - View as HTML - All 6 versions
- ►nih.gov J Chen, L Wang, Y Chen, P Sternberg, J Cai - Investigative ophthalmology & visual science, 2009 - ARVO METHODS. Cultured ARPE-19 cells were treated with different concentrations of
4-HNE and a PI3K inhibitor, LY294002. Intracellular glutathione (GSH) was
measured by high-performance liquid chromatography (HPLC). The ... Cited by 1 - Related articles - All 5 versions
RV Rajala, ME McClellan, JD Ash, RE … - Advances in experimental medicine and biology, 2003 - ncbi.nlm.nih.gov 1: Adv Exp Med Biol. 2003;533:369-76. Regulation of retinal phosphoinositide
3-kinase activity in p85alpha-subunit knockout mice. ... Cited by 1 - Related articles - BL Direct
RV Rajala, I Ivanovic, AK Dilly - Vitamins and hormones, 2009 - ncbi.nlm.nih.gov In the diabetic eye, the increased accumulation of sorbitol in the retina has
been implicated in the pathogenesis of diabetic retinopathy (DR).
Neurodegeneration is an important component of DR as demonstrated by ... Cited by 1 - Related articles
H Wu, S Ichikawa, C Tani, B Zhu, M Tada, Y … - BBA-Molecular and Cell Biology of Lipids, 2009 - Elsevier Docosahexaenoic acid (22: 6n-3; DHA) is a long chain polyunsaturated fatty acid
that exists highly enriched in fish oil, and it is one of the low molecular
weight food chemicals which can pass a blood brain barrier. A preliminary ... Cited by 1 - Related articles - All 2 versions
W Wang, A Fridman, W Blackledge, S Connelly … - Journal of Biological Chemistry, 2009 - ASBMB The phosphatidylinositol 3-kinase (PI3K)/Akt signaling pathway is highly
conserved throughout evolution and regulates cell size and survival and cell
cycle progression. It regulates the latter by stimulating procession ... Cited by 1 - Related articles - All 3 versions
