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Scholar Results 1 - 10 of about 101 related to Freathy: Type 2 diabetes risk alleles are associated with reduced size at birth. (0.10 sec) 

Type 2 diabetes risk alleles are associated with reduced size at birth

- diabetesjournals.org
RM Freathy, AJ Bennett, SM Ring, B Shields, … - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Low birth weight is associated with an increased risk of type 2
diabetes. The mechanisms underlying this association are unknown and may
represent intrauterine programming or two phenotypes of one genotype. The ...
Cited by 7 - Related articles - All 4 versions

Interaction between prenatal growth and high-risk genotypes in the development of type 2 …


N Pulizzi, V Lyssenko, A Jonsson, C Osmond, … - Diabetologia, 2009 - Springer
Page 1. SHORT COMMUNICATION Interaction between prenatal growth and high-risk
genotypes in the development of type 2 diabetes N. Pulizzi ...
Cited by 3 - Related articles - All 5 versions

No evidence that established type 2 diabetes susceptibility variants in the PPARG and …


AJ Bennett, U Sovio, A Ruokonen, H Martikainen … - Diabetologia, 2008 - Springer
Abstract Aims/hypothesis The P12A variant in the PPARG gene and the E23K
polymorphism in KCNJ11 are both known to influence individual predisposition to
type 2 diabetes. If the effect of these variants on insulin secretion and ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Adult Metabolic Syndrome and Impaired Glucose Tolerance Are Associated With Different …

- diabetesjournals.org
CHD Fall, HS Sachdev, C Osmond, R Lakshmy … - Diabetes care, 2008 - Am Diabetes Assoc
RESULTS—Men and women with metabolic syndrome (29% overall), any of its
component features, or higher (greater than upper quartile) insulin resistance
(homeostasis model assessment) had more rapid BMI or weight gain than the ...
Cited by 2 - Related articles - All 3 versions

Variation in the IGF1 gene and growth in foetal life and infancy. The Generation R Study


JJ Geelhoed, DO Mook-Kanamori, J Witteman … - Clinical endocrinology, 2008 - pt.wkhealth.com
JJ Miranda Geelhoed*†, Dennis O. Mook-Kanamori*†, Jacqueline CM Witteman†,
Albert Hofman†, Cornelia M. van Duijn†, Henriëtte A. Moll*§, Eric AP
Steegers‡, Anita CS Hokken-Koelega§ and Vincent WV Jaddoe*†§
Cited by 5 - Related articles - BL Direct - All 6 versions

Relationship between fractional pancreatic beta cell area and fasting plasma glucose …


Y Saisho, AE Butler, E Manesso, R Galasso, L … - Diabetologia - Springer
Abstract Aims/hypothesis We sought to establish the relationship between fasting
plasma glucose concentrations and pancreatic fractional beta cell area in adult
cynomolgus monkeys (Macaca fascicularis). Methods Fasting plasma glucose ...
Related articles

[PDF] Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene


SFA Grant, H Hakonarson - med.upenn.edu
Page 1. Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight
gene Jianhua Zhao 1 , Mingyao Li 2 , Jonathan P. Bradfield ...
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The long lifespan and low turnover of human islet beta cells estimated by mathematical …


M Cnop, SJ Hughes, M Igoillo-Esteve, MB … - Diabetologia - Springer
Abstract Aims/hypothesis Defects in pancreatic beta cell turnover are implicated
in the pathogenesis of type 2 diabetes by genetic markers for diabetes.
Decreased beta cell neogenesis could contribute to diabetes. The longevity ...
Related articles - All 2 versions

Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth …


DO Mook-Kanamori, SWK de Kort, CM van … - BMC Medical Genetics, 2009 - pubmedcentral.nih.gov
An inverse association between birth weight and the risk of developing type 2
diabetes (T2D) in adulthood has been reported. This association may be explained
by common genetic variants related to insulin secretion and resistance, ...
Related articles - All 4 versions

Commentary: A new dawn for genetic epidemiology?


TM Frayling - International Journal of Epidemiology, 2009 - IEA
Genome-wide association studies (GWAS) have resulted in an unprecedented leap in
our understanding of the common genetic variation associated with common
diseases and traits. Work performed predominantly in the last 2 years means ...
Related articles - All 5 versions


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