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Scholar Results 1 - 10 of about 101 related to Sparsø: G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting.... (0.11 sec) 

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired …

- diabetesjournals.org
T Sparsø, A Bonnefond, E Andersson, N Bouatia-Naji, J … - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Genome-wide association studies have identified several variants within the MTNR1B
locus that are associated with fasting plasma glucose (FPG) and type 2 diabetes. We refined
the association signal by direct genotyping and examined for associations of the variant ...
Cited by 4 - Related articles - All 3 versions

Combined analysis of 19 common validated type 2 diabetes susceptibility gene …


T Sparsø, N Grarup, C Andreasen, A Albrechtsen, J … - Diabetologia, 2009 - Springer
Abstract Aims/hypothesis The list of validated type 2 diabetes susceptibility variants has recently
been expanded from three to 19. The variants identified are common and have low penetrance
in the general population. The aim of the study is to investigate the combined effect of the ...
Cited by 2 - Related articles - All 2 versions

Dietary patterns predict changes in two-hour post-oral glucose tolerance test …


C Lau, U Toft, I Tetens, B Carstensen, T Jorgensen … - Journal of …, 2009 - Am Soc Nutrition
We examined whether the adherence to major dietary patterns at baseline of 5824 nondiabetic
Danes (30–60 y) enrolled in the nonpharmacological Inter99 intervention predicted changes
in fasting plasma glucose (FPG) and postchallenge 2-h plasma glucose (2h-PG) ...
Cited by 2 - Related articles - All 4 versions

Use of labeled oral minimal model to measure hepatic insulin sensitivity

- physiology.org
CD Man, G Toffolo, R Basu, RA Rizza, C … - American Journal of …, 2008 - Am Physiological Soc
The ability to accurately quantify indexes of the individual role of glucose (GE L ) and insulin
(S I L ) in the suppression of endogenous glucose production (EGP) would improve the understanding
of liver metabolism. Measuring these indexes during an IVGTT by minimal modeling of ...
Cited by 1 - Related articles - All 3 versions

Erythropoietic stress and anemia in diabetes mellitus


DK Singh, P Winocour, K Farrington - Nature Reviews Endocrinology, 2009 - nature.com
Anemia is one of the world's most common preventable conditions, yet it is often overlooked,
especially in people with diabetes mellitus. Diabetes-related chronic hyperglycemia can lead
to a hypoxic environment in the renal interstitium, which results in impaired production of ...
Cited by 1 - Related articles - All 3 versions

SIRT1 and insulin resistance


F Liang, S Kume, D Koya - Nature Reviews Endocrinology, 2009 - nature.com
Sirtuin 1 (SIRT1), the mammalian homolog of SIR2, was originally identified as a NAD-dependent
histone deacetylase, the activity of which is closely associated with lifespan under calorie
restriction. Growing evidence suggests that SIRT1 regulates glucose or lipid metabolism ...
Cited by 2 - Related articles - All 3 versions

Absence of an acute insulin response predicts onset of type 2 diabetes in a …

- endojournals.org
G Nijpels, W Boorsma, JM Dekker, F Hoeksema … - Journal of Clinical …, 2008 - Endocrine Soc
Context: In persons with impaired glucose tolerance (IGT), both impaired insulin secretion and
insulin resistance contribute to the conversion to type 2 diabetes mellitus (T2DM). However, few
studies have used criterion standard measures to asses the predictive value of impaired ...
Cited by 1 - Related articles - All 4 versions

free-living physical activity energy expenditure is strongly related to glucose …

- diabetesjournals.org
FK Assah, U Ekelund, S Brage, JC Mbanya, NJ … - Diabetes Care, 2009 - Am Diabetes Assoc
RESULTS—There was a significant negative correlation between PAEE and 2-h glucose (r =
–0.43; P = 0.01) but not fasting glucose (r = 0.1; P = 0.57). The inverse association between PAEE
and 2-h glucose remained after adjustment for age, sex, smoking, alcohol consumption, ...
Cited by 1 - Related articles - All 3 versions

Natural History of Insulin Sensitivity and Insulin Secretion in the Progression From …

- diabetesjournals.org
K Færch, A Vaag, JJ Holst, T Hansen, T Jørgensen, … - Diabetes Care, 2009 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS—Baseline and 5-year follow-up data from the Inter99
study were used. Individuals with normal glucose tolerance (NGT) at baseline and i-IFG,
i-IGT, combined IFG/IGT, or NGT at the 5-year follow-up were examined with an oral ...
Cited by 3 - Related articles - All 3 versions

Predictors of future fasting and 2-hour post-OGTT plasma glucose levels in middle- …


K Færch, A Vaag, DR Witte, T Jørgensen, O … - Diabet Med, 2009 - interscience.wiley.com
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Cited by 2 - Related articles - All 3 versions


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