S Satofuka, A Ichihara, N Nagai, K Noda, Y … - Diabetes, 2009 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS Long-Evans rats, C57BL/6 mice, and angiotensin II
type 1 receptor (AT1-R)-deficient mice with streptozotocin-induced diabetes were
treated with (pro)renin receptor blocker (PRRB). Retinal mRNA expression of ... Cited by 1 - Related articles - All 3 versions
MH Lee, HK Song, GJ Ko, YS Kang, SY Han, … - Kidney international, 2008 - nature.com Adipose tissue is recognized as a pivotal organ in the development of insulin
resistance. This study seeks to determine the effect of angiotensin receptor
blockade (ARB) on insulin resistance of adipocytes in culture and in a rat ... Cited by 4 - Related articles - All 5 versions
- ►physoc.org Z Shan, AE Cuadra, C Sumners, MK Raizada - Experimental Physiology, 2008 - Physiological Soc (Pro)renin receptor (PRR), the newest member of the renin–angiotensin system
(RAS), is turning out to be an important player in the regulation of the
cardiovascular system. It plays a pivotal role in activation of the local ... Cited by 9 - Related articles - BL Direct - All 11 versions
Y Nagai, A Ichihara, D Nakano, S Kimura, N … - Experimental Physiology, 2009 - Physiological Soc Recent studies have shown that blocking non-proteolytically activated prorenin
with a decoy peptide for the handle region of the prorenin prosegment (HRP)
inhibits the development of microvascular complications in diabetic ... Related articles - All 9 versions
M Takada, N Ura, K Higashiura, H Murakami, … - Hypertension research: official journal of the Japanese …, 2001 - ncbi.nlm.nih.gov The aim of this study was to examine the roles of muscle fiber composition,
capillary density and muscle blood flow in insulin resistance (IR) and the
effect of cilnidipine, a calcium channel blocker in fructose-fed rats ... Cited by 12 - Related articles - BL Direct - All 3 versions
- ►physiology.org V Achard, S Boullu-Ciocca, R Desbriere, G … - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc Adipose tissue synthesizes all components of the renin-angiotensin system. The
renin receptor (RenR) is able, on renin binding, to increase its efficiency to
generate angiotensin I from angiotensinogen. We demonstrate that RenR is ... Cited by 15 - Related articles - BL Direct - All 6 versions
YY Fan, R Baba, Y Nagai, A Miyatake, N … - Hypertension Research, 2006 - nature.com Recent studies have suggested that aldosterone plays a role in the pathogenesis
of renal injury. In this study, we investigated whether local angiotensin II
(Ang II) activity contributes to the progression of renal injury in ... Cited by 18 - Related articles - BL Direct - All 5 versions
[CITATION] Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid- …
A Ichihara, Y Kaneshiro, F Suzuki - Expert Opin. Investig. Drugs, 2006 - informahealthcare.com When the 'handle region' of the prorenin prosegment interacts with the
(pro)renin receptor, the prorenin molecule partially changes the conformation to
an enzymatically active state. On the other hand, the receptor triggers its ... Cited by 20 - Related articles - BL Direct - All 6 versions
- ►physiology.org Y Wei, K Chen, AT Whaley-Connell, CS Stump … - … Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc The cardiometabolic syndrome (CMS), with its increased risk for cardiovascular
disease (CVD), nonalcoholic fatty liver disease (NAFLD), and chronic kidney
disease (CKD), has become a growing worldwide health problem. Insulin ... Cited by 31 - Related articles - BL Direct - All 3 versions
