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Scholar Results 1 - 10 of about 61 related to Roxburgh: Allelic depletion of grem1 attenuates diabetic kidney disease. (0.12 sec) 

Allelic depletion of grem1 attenuates diabetic kidney disease


SA Roxburgh, JJ Kattla, SP Curran, YM O' … - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Gremlin (grem1) is an antagonist of the bone morphogenetic protein
family that plays a key role in limb bud development and kidney formation. There
is a growing appreciation that altered grem1 expression may regulate the ...
Cited by 1 - Related articles - All 3 versions

Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic …


G Carvajal, A Droguett, ME Burgos, C Aros, L … - Transplantation proceedings, 2008 - Elsevier
BACKGROUND: Chronic allograft nephropathy (CAN) is the most frequent cause of
chronic dysfunction and late loss of renal allografts. Epithelial mesenchymal
transition (EMT) has been identified as responsible for the presence of ...
Cited by 5 - Related articles - All 21 versions

High-density lipoproteins affect endothelial BMP-signaling by modulating expression of the …

- nih.gov
Y Yao, ES Shao, M Jumabay, A Shahbazian, S … - Arteriosclerosis, thrombosis, and vascular biology, 2008 - Am Heart Assoc
Methods and Results— Increasing concentrations of HDL progressively enhanced
expression of the activin-like kinase receptor (ALK)1 and ALK2 in human aortic
endothelial cells as determined by real-time polymerase chain reaction and ...
Cited by 5 - Related articles - All 9 versions

Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein …


G Lagna, MM Ku, PH Nguyen, NA Neuman, BN … - Journal of Biological Chemistry, 2007 - ASBMB
Vascular smooth muscle cells (VSMCs), unlike other muscle cells, do not
terminally differentiate. In response to injury, VSMCs change phenotype,
proliferate, and migrate as part of the repair process. Dysregulation of ...
Cited by 4 - Related articles - All 4 versions

Smooth muscle cells give rise to osteochondrogenic precursors and chondrocytes in …

- prsjournal.net
MY Speer, HY Yang, T Brabb, E Leaf, A Look, … - Circulation research, 2009 - Am Heart Assoc
Kluwer Health, 351 West Camden Street, Baltimore, MD 21202-2436. Phone:
410-528-4050. Permissions: Permissions & Rights Desk, Lippincott Williams &
Wilkins, a division of Wolters ... Smooth Muscle Cells Give Rise to ...
Cited by 5 - Related articles - All 7 versions

Inhibitory Smad transcription factors protect arterial endothelial cells from apoptosis …


M Kiyono, M Shibuya - Oncogene, 2006 - nature.com
Arterial endothelial cells (EC) at the adult stage differ from capillary and
venous EC in terms of resistance to stress; however, the molecular basis of this
resistance is not clear. Here, we found that arterial EC are highly ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Expression of BMP-7 and USAG-1 (a BMP antagonist) in kidney development and injury


M Tanaka, S Endo, T Okuda, AN Economides, … - Kidney International, 2007 - nature.com
Once developed, end-stage renal disease cannot be reversed by any current
therapy. Bone morphogenetic protein-7 (BMP-7), however, is a possible treatment
for reversing end-stage renal disease. Previously, we showed that the BMP ...
Cited by 7 - Related articles - BL Direct - All 3 versions

Gremlin promotes vascular smooth muscle cell proliferation and migration


TT Maciel, RS Melo, N Schor, AH Campos - Journal of Molecular and Cellular Cardiology, 2008 - Elsevier
Recent reports highlight the importance of BMP in the vasculature. We
investigated the expression pattern and role of the BMP antagonist gremlin in
VSMC. We detected gremlin mRNA constitutive expression in adult and ...
Cited by 10 - Related articles - All 17 versions

Bone morphogenetic protein (BMP) type II receptor is required for BMP-mediated growth …


PB Yu, DY Deng, H Beppu, CC Hong, C Lai, … - Journal of Biological Chemistry, 2008 - ASBMB
Bone morphogenetic protein (BMP) signals regulate the growth and differentiation
of diverse lineages. The association of mutations in the BMP type II receptor
(BMPRII) with idiopathic pulmonary arterial hypertension suggests an ...
Cited by 9 - Related articles - All 3 versions

Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents …

- oxfordjournals.org
S Mezzano, A Droguett, ME Burgos, C Aros, L … - Nephrology Dialysis Transplantation, 2007 - ERA-EDTA
Background. Recent evidence in vitro and in vivo suggests that gremlin, a bone
morphogenetic protein antagonist, is participating in tubular epithelial
mesenchymal transition (EMT) in diabetic nephropathy as a downstream ...
Cited by 10 - Related articles - BL Direct - All 5 versions


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