- ►diabetesjournals.org G Simon, M Parker, V Ramiya, C Wasserfall, Y Huang, … - Diabetes, 2008 - Am Diabetes Assoc RESULTS—We observed that mATG attenuates type 1 diabetes development in an age-dependent
fashion, only proving efficacious at disease onset or in the late pre-diabetic phase (12 weeks
of age). When provided at 12 weeks of age, mATG reversed pancreatic insulitis, improved ... Cited by 10 - Related articles - BL Direct - All 5 versions
- ►hematologylibrary.org MC Ruzek, JS Waire, D Hopkins, G LaCorcia … - …, 2008 - bloodjournal.hematologylibrary.org Antithymocyte/antilymphocyte globulins are polyclonal antihuman T-cell antibodies used clinically
to treat acute transplant rejection. These reagents deplete T cells, but a rabbit antihuman thymocyte
globulin has also been shown to induce regulatory T cells in vitro. To examine whether ... Cited by 8 - Related articles - BL Direct - All 2 versions
- ►turkiyeklinikleri.com [PDF] AL Tang, DL Farber - Current Opinion in Organ Transplantation, 2007 - journals.lww.com Recent findings: Memory T cells are generated against alloantigens via homologous and
cross-reactive priming, and recent studies demonstrate that T-cell depletion can also paradoxically
result in memory generation. While initially thought to be impervious to regulation due to ... Cited by 2 - Related articles - BL Direct - All 7 versions
RE Greenlaw, NJ Gardner, CA Farrar, H … - American Journal of …, 2008 - interscience.wiley.com Memory T cells are the very essence of adaptive immunity with their rapid and efficient response
to antigen rechallenge and long-term persistence. However, it is becoming increasingly evident
that when primed with self or transplanted tissue, these cells play a key role in causing ... Cited by 2 - Related articles - All 3 versions
G Fousteri, D Bresson, M von Herrath - Advances in experimental medicine …, 2007 - Springer Abstract. Administration of autoantigens, especially via the mucosal route, can induce toler- ance
under certain circumstances. In autoimmune diabetes, mucosal vaccination with autoan- tigens
was frequently effective in restoring tolerance in mice but has not yet succeeded in ... Cited by 3 - Related articles - BL Direct - All 5 versions
JF Purton, J Sprent, CD Surh - European Journal of Immunology - interscience.wiley.com The immune system must maintain a broad repertoire of naïve T cells in order to respond to the
diverse range of pathogens that it will encounter over the course of a lifetime. Although it is known
that contact with IL-7 is crucial for the survival of naïve T cells, the precise intracellular ... Cited by 4 - Related articles - BL Direct - All 4 versions
MF Bevans, RA Shalabi - Clinical Journal of Oncology Nursing, 2004 - Onc Nurs Society Antithymocyte globulin (ATG) is used commonly in pa- tients with severe aplastic anemia and
those undergoing renal transplant. Its utility also is being explored in the treatment of myelodysplastic
syndrome, conditioning regi- mens for hematopoietic stem cell transplant, and prophy- ... Cited by 5 - Related articles - BL Direct - All 2 versions
A Bacigalupo - Current opinion in hematology, 2005 - journals.lww.com Recent findings: The review shows that antithymocyte globulin is used frequently in Europe in
the setting of unrelated or family mismatched donor transplants. This may not be the case for
American centers, reluctant to introduce antithymocyte globulin possibly due to known ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] H Bour-Jordan, JA Bluestone - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Autoimmune diabetes is believed to be mediated primarily by T cells. However, B cells have
been implicated in the pathogenesis of the disease in NOD mice. Although preclinical studies
have been limited by the absence of anti-CD20 reagents that can induce B cell depletion ... Cited by 9 - Related articles - BL Direct - All 5 versions
